Extracorporeal membrane oxygenation in the treatment of inhalation injuries

G. O'Toole, Giles J. Peek, W. Jaffe, D. Ward, H. Henderson, R. K. Firmin

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Smoke inhalation is a leading cause of death in burns patients. Conventional ventilation cannot always maintain adequate tissue oxygenation. Extracorporeal membrane oxygenation (ECMO) has rarely been used in the treatment of smoke inhalation injuries. ECMO is a proven therapy in severe neonatal respiratory failure and has also been used to good effect in the treatment of children and adults. We report the cases of two children who developed severe respiratory failure refractory to maximal ventilation, one case followed smoke inhalation alone, the other followed smoke inhalation and burns. Pre-ECMO PaO 2/FIO 2 ratios were 6.5 and 8 kPa, respectively. The patients were treated with veno-venous ECMO for 72 and 144 h, respectively. The use of ECMO for respiratory failure due to smoke inhalation and thermal injury is discussed.

Original languageEnglish (US)
Pages (from-to)562-565
Number of pages4
JournalBurns
Volume24
Issue number6
DOIs
StatePublished - Sep 1998
Externally publishedYes

Fingerprint

Extracorporeal Membrane Oxygenation
Inhalation
Smoke Inhalation Injury
Smoke
Respiratory Insufficiency
Wounds and Injuries
Ventilation
Inhalation Burns
Therapeutics
Burns
Cause of Death
Hot Temperature

Keywords

  • ARDS
  • Burns
  • ECMO
  • Inhalation injury
  • Paediatric
  • Survival

ASJC Scopus subject areas

  • Emergency Medicine
  • Surgery

Cite this

O'Toole, G., Peek, G. J., Jaffe, W., Ward, D., Henderson, H., & Firmin, R. K. (1998). Extracorporeal membrane oxygenation in the treatment of inhalation injuries. Burns, 24(6), 562-565. https://doi.org/10.1016/S0305-4179(98)00061-8

Extracorporeal membrane oxygenation in the treatment of inhalation injuries. / O'Toole, G.; Peek, Giles J.; Jaffe, W.; Ward, D.; Henderson, H.; Firmin, R. K.

In: Burns, Vol. 24, No. 6, 09.1998, p. 562-565.

Research output: Contribution to journalArticle

O'Toole, G, Peek, GJ, Jaffe, W, Ward, D, Henderson, H & Firmin, RK 1998, 'Extracorporeal membrane oxygenation in the treatment of inhalation injuries', Burns, vol. 24, no. 6, pp. 562-565. https://doi.org/10.1016/S0305-4179(98)00061-8
O'Toole G, Peek GJ, Jaffe W, Ward D, Henderson H, Firmin RK. Extracorporeal membrane oxygenation in the treatment of inhalation injuries. Burns. 1998 Sep;24(6):562-565. https://doi.org/10.1016/S0305-4179(98)00061-8
O'Toole, G. ; Peek, Giles J. ; Jaffe, W. ; Ward, D. ; Henderson, H. ; Firmin, R. K. / Extracorporeal membrane oxygenation in the treatment of inhalation injuries. In: Burns. 1998 ; Vol. 24, No. 6. pp. 562-565.
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