Expression of Concern: Human cardiac stem cell differentiation is regulated by a mircrine mechanism (Circulation Research (2011) 123 (1287-1296) DOI: 10.1161/CIRCULATIONAHA.110.982918)

T. Hosoda, H. Zheng, M. Cabral-Da-Silva, F. Sanada, N. Ide-Iwata, B. Ogórek, J. Ferreira-Martins, C. Arranto, D. D'Amario, F. Del Monte, K. Urbanek, D. A. D'Alessandro, R. E. Michler, P. Anversa, M. Rota, J. Kajstura, A. Leri

Research output: Contribution to journalComment/debate

Abstract

Harvard Medical School and Brigham and Women's Hospital (BWH) have notified the American Heart Association that they have completed a review into concerns about the integrity of certain data generated in a former laboratory at BWH. The review concluded that there were issues with data reported in the following publications: 1. Circ Res. 2008;102:597-606 2. Circ Res. 2009;105:1128-1140 3. Circ Res. 2010;107:305-315 4. Circ Res. 2010;107:800-809 5. Circ Res. 2010;107:1374-1386 6. Circ Res. 2011;108:1071-1083 7. Circ Res. 2011;108:1467-1481 8. Circ Res. 2011;109:941-961 9. Circ Res. 2012;111:152-155 10. Circ Res. 2012;110:701-715 11. Circ Res. 2012;111:894-906 12. Circ Res. 2012;111:1286-1296 13. Circulation. 2011;123:1287-1296 14. Circulation. 2013;128:2211-2223 15. Circulation. 2014;129:157-172 We are communicating with the authors of these publications as well as Harvard Medical School. We are publishing this Expression of Concern while we await the outcome of these communications and to indicate that the data in the listed publications may not be reliable. N.A. Mark Estes III, MD Chairperson, AHA Scientific Publishing Committee This Expression of Concern is copublished in Circulation and Circulation Research.

Original languageEnglish (US)
Pages (from-to)e4-e5
JournalCirculation research
Volume124
Issue number2
DOIs
StatePublished - Jan 18 2019

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Cell Differentiation
Stem Cells
Medical Schools
Research
Communication

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Expression of Concern : Human cardiac stem cell differentiation is regulated by a mircrine mechanism (Circulation Research (2011) 123 (1287-1296) DOI: 10.1161/CIRCULATIONAHA.110.982918). / Hosoda, T.; Zheng, H.; Cabral-Da-Silva, M.; Sanada, F.; Ide-Iwata, N.; Ogórek, B.; Ferreira-Martins, J.; Arranto, C.; D'Amario, D.; Del Monte, F.; Urbanek, K.; D'Alessandro, D. A.; Michler, R. E.; Anversa, P.; Rota, M.; Kajstura, J.; Leri, A.

In: Circulation research, Vol. 124, No. 2, 18.01.2019, p. e4-e5.

Research output: Contribution to journalComment/debate

Hosoda, T, Zheng, H, Cabral-Da-Silva, M, Sanada, F, Ide-Iwata, N, Ogórek, B, Ferreira-Martins, J, Arranto, C, D'Amario, D, Del Monte, F, Urbanek, K, D'Alessandro, DA, Michler, RE, Anversa, P, Rota, M, Kajstura, J & Leri, A 2019, 'Expression of Concern: Human cardiac stem cell differentiation is regulated by a mircrine mechanism (Circulation Research (2011) 123 (1287-1296) DOI: 10.1161/CIRCULATIONAHA.110.982918)', Circulation research, vol. 124, no. 2, pp. e4-e5. https://doi.org/10.1161/RES.0000000000000241
Hosoda, T. ; Zheng, H. ; Cabral-Da-Silva, M. ; Sanada, F. ; Ide-Iwata, N. ; Ogórek, B. ; Ferreira-Martins, J. ; Arranto, C. ; D'Amario, D. ; Del Monte, F. ; Urbanek, K. ; D'Alessandro, D. A. ; Michler, R. E. ; Anversa, P. ; Rota, M. ; Kajstura, J. ; Leri, A. / Expression of Concern : Human cardiac stem cell differentiation is regulated by a mircrine mechanism (Circulation Research (2011) 123 (1287-1296) DOI: 10.1161/CIRCULATIONAHA.110.982918). In: Circulation research. 2019 ; Vol. 124, No. 2. pp. e4-e5.
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abstract = "Harvard Medical School and Brigham and Women's Hospital (BWH) have notified the American Heart Association that they have completed a review into concerns about the integrity of certain data generated in a former laboratory at BWH. The review concluded that there were issues with data reported in the following publications: 1. Circ Res. 2008;102:597-606 2. Circ Res. 2009;105:1128-1140 3. Circ Res. 2010;107:305-315 4. Circ Res. 2010;107:800-809 5. Circ Res. 2010;107:1374-1386 6. Circ Res. 2011;108:1071-1083 7. Circ Res. 2011;108:1467-1481 8. Circ Res. 2011;109:941-961 9. Circ Res. 2012;111:152-155 10. Circ Res. 2012;110:701-715 11. Circ Res. 2012;111:894-906 12. Circ Res. 2012;111:1286-1296 13. Circulation. 2011;123:1287-1296 14. Circulation. 2013;128:2211-2223 15. Circulation. 2014;129:157-172 We are communicating with the authors of these publications as well as Harvard Medical School. We are publishing this Expression of Concern while we await the outcome of these communications and to indicate that the data in the listed publications may not be reliable. N.A. Mark Estes III, MD Chairperson, AHA Scientific Publishing Committee This Expression of Concern is copublished in Circulation and Circulation Research.",
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AU - Hosoda, T.

AU - Zheng, H.

AU - Cabral-Da-Silva, M.

AU - Sanada, F.

AU - Ide-Iwata, N.

AU - Ogórek, B.

AU - Ferreira-Martins, J.

AU - Arranto, C.

AU - D'Amario, D.

AU - Del Monte, F.

AU - Urbanek, K.

AU - D'Alessandro, D. A.

AU - Michler, R. E.

AU - Anversa, P.

AU - Rota, M.

AU - Kajstura, J.

AU - Leri, A.

PY - 2019/1/18

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N2 - Harvard Medical School and Brigham and Women's Hospital (BWH) have notified the American Heart Association that they have completed a review into concerns about the integrity of certain data generated in a former laboratory at BWH. The review concluded that there were issues with data reported in the following publications: 1. Circ Res. 2008;102:597-606 2. Circ Res. 2009;105:1128-1140 3. Circ Res. 2010;107:305-315 4. Circ Res. 2010;107:800-809 5. Circ Res. 2010;107:1374-1386 6. Circ Res. 2011;108:1071-1083 7. Circ Res. 2011;108:1467-1481 8. Circ Res. 2011;109:941-961 9. Circ Res. 2012;111:152-155 10. Circ Res. 2012;110:701-715 11. Circ Res. 2012;111:894-906 12. Circ Res. 2012;111:1286-1296 13. Circulation. 2011;123:1287-1296 14. Circulation. 2013;128:2211-2223 15. Circulation. 2014;129:157-172 We are communicating with the authors of these publications as well as Harvard Medical School. We are publishing this Expression of Concern while we await the outcome of these communications and to indicate that the data in the listed publications may not be reliable. N.A. Mark Estes III, MD Chairperson, AHA Scientific Publishing Committee This Expression of Concern is copublished in Circulation and Circulation Research.

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