Exploring the usage of a mobile phone application in transplanted patients to encourage medication compliance and education

Alana Zanetti-Yabur, Amanda Rizzo, Nicole A.M. Hayde, Anthony C. Watkins, Juan P. Rocca, Jay A. Graham

Research output: Contribution to journalArticle

9 Scopus citations


Background: Medication non-adherence in transplant patients is a grave problem that results in increased rejection episodes, graft loss and significant morbidity. Methods: The efficacy of users and non-users of a mobile phone application (mobile app) in promoting medication adherence was investigated. The Beliefs about Medicine Questionnaire (BMQ) and Morisky Medication Adherence Scale (MMAS-8) were used in these cohorts to assess the predilection for poor adherence. Serum tacrolimus, creatinine levels, and rejection episodes were also recorded. Lastly, the patients were tested on their recall of their immunosuppression. Results: Overall, patients had extremely negative beliefs about medication reflected in their tendency toward higher predicted rates of non-adherence. Interestingly, though not significant, app users had higher rates of medication recollection. Conclusions: The high-risk nature of this population demands efforts to abrogate non-adherence. Caregivers are charged with the responsibility to offer patients a feasible option to safeguard treatment compliance. Mobile apps are a potentially powerful tool, which can be used to decrease non-adherence.

Original languageEnglish (US)
JournalAmerican Journal of Surgery
Publication statusAccepted/In press - Aug 23 2016



  • IPhone
  • Kidney transplant
  • Liver transplant
  • Medication adherence
  • Mobile phone application
  • Patient education

ASJC Scopus subject areas

  • Surgery

Cite this