In this issue of Molecular Cell, Cao et al. (2021) report that AML cells are specifically addicted to an IRF8-MEF2D gene expression network. Furthermore, they identify a chromatin reader, ZMYND8, as the upstream regulator of the IRF8-MEF2D program whose activity is critical for AML cell survival.
|Original language||English (US)|
|Number of pages||2|
|State||Published - Sep 2 2021|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology