Experimental bilateral carotid artery occlusion: A study of the optic nerve in the rat

J. Takamatsu, A. Hirano, D. Levy, P. Henkind

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The presence of marked changes in the neural retina and retinal vessels of Long-evans pigmented rat following bilateral carotid ligation has been previously documented by serial ophthalmologic examinations. Light and electron microscopic studies of the optic nerve in this experimental animal model revealed advanced optic nerve atrophy in ten of twelve rats examined. There was no significant pathology in either the retina or optic nerve in the remaining two rats after carotid ligation or in the sham operated controls.

Original languageEnglish (US)
Pages (from-to)423-428
Number of pages6
JournalNeuropathology and Applied Neurobiology
Volume10
Issue number6
StatePublished - 1984

Fingerprint

Optic Nerve
Carotid Arteries
Ligation
Retina
Optic Atrophy
Retinal Vessels
Long Evans Rats
Animal Models
Electrons
Pathology
Light

ASJC Scopus subject areas

  • Clinical Neurology
  • Pathology and Forensic Medicine
  • Neuroscience(all)

Cite this

Experimental bilateral carotid artery occlusion : A study of the optic nerve in the rat. / Takamatsu, J.; Hirano, A.; Levy, D.; Henkind, P.

In: Neuropathology and Applied Neurobiology, Vol. 10, No. 6, 1984, p. 423-428.

Research output: Contribution to journalArticle

Takamatsu, J, Hirano, A, Levy, D & Henkind, P 1984, 'Experimental bilateral carotid artery occlusion: A study of the optic nerve in the rat', Neuropathology and Applied Neurobiology, vol. 10, no. 6, pp. 423-428.
Takamatsu, J. ; Hirano, A. ; Levy, D. ; Henkind, P. / Experimental bilateral carotid artery occlusion : A study of the optic nerve in the rat. In: Neuropathology and Applied Neurobiology. 1984 ; Vol. 10, No. 6. pp. 423-428.
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