EXPERIMENTAL BILATERAL CAROTID ARTERY OCCLUSION: A STUDY OF THE OPTIC NERVE IN THE RAT

J. TAKAMATSU, A. HIRANO, D. LEVY, P. HENKIND

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Experimental bilateral carotid artery occlusion: a study of the optic nerve in the rat The presence of marked changes in the neural retina and retinal vessels of Long‐Evans pigmented rat following bilateral carotid ligation has been previously documented by serial ophthalmologic examinations. Light and electron microscopic studies of the optic nerve in this experimental animal model revealed advanced optic nerve atrophy in ten of twelve rats examined. There was no significant pathology in either the retina or optic nerve in the remaining two rats after carotid ligation or in the sham‐operated controls.

Original languageEnglish (US)
Pages (from-to)423-428
Number of pages6
JournalNeuropathology and Applied Neurobiology
Volume10
Issue number6
DOIs
StatePublished - Nov 1984

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

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