Abstract
In this review, we describe how normal ageing may involve the acquisition of epigenetic errors over time, akin to the accumulation of genetic mutations with ageing. We describe how such experiments are currently performed, their limitations technically and analytically and their application to ageing research.
Original language | English (US) |
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Pages (from-to) | 255-268 |
Number of pages | 14 |
Journal | Experimental Gerontology |
Volume | 45 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2010 |
Keywords
- Aging
- Chromatin
- DNA methylation
- Epigenetic
- Microarray
ASJC Scopus subject areas
- Biochemistry
- Aging
- Molecular Biology
- Genetics
- Endocrinology
- Cell Biology