Experience with sonography as an adjunct to amniocentesis for prenatal diagnosis of fetal genetic disorders

Prasanta Chandra, Harold M. Nitowsky, Robert W. Marion, Mordecai Koenigsberg, Eva Taben, H. Wallace Kava

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

This report summarized our experience with a consecutive series of 800 women referred for midtrimester amniocentesis for prenatal diagnosis of a fetal genetic abnormality. The results are compared before and after introduction of sonography immediately prior to the tap as a routine adjunct of the procedure. Following use of sonography there was a statistically significant reduction in the frequency of bloody taps, and an increase in the proportion of successful and informative initial taps. Moreover, in many instances sonography provided information useful for identification of fetal abnormalities or for management of pregnancy. These findings support the recommendation that examination by sonography should be utilized routinely as an adjunct to amniocentesis, despite the uncertainties relating to possible long-term adverse effects of intrauterine exposure to ultrasound.

Original languageEnglish (US)
Pages (from-to)519-524
Number of pages6
JournalAmerican Journal of Obstetrics and Gynecology
Volume133
Issue number5
StatePublished - Mar 1 1979

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Inborn Genetic Diseases
Amniocentesis
Prenatal Diagnosis
Ultrasonography
Second Pregnancy Trimester
Uncertainty
Pregnancy

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Experience with sonography as an adjunct to amniocentesis for prenatal diagnosis of fetal genetic disorders. / Chandra, Prasanta; Nitowsky, Harold M.; Marion, Robert W.; Koenigsberg, Mordecai; Taben, Eva; Kava, H. Wallace.

In: American Journal of Obstetrics and Gynecology, Vol. 133, No. 5, 01.03.1979, p. 519-524.

Research output: Contribution to journalArticle

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