Experience with autologous bone marrow harvesting and transfusion of marrow-derived red cells

N. Ciobanu, V. Weinberg, Joseph A. Sparano, G. Zervos, J. Walewski, M. Spivack, P. H. Wiernik

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Marrow red cells (MRBCs) from 56 autologous bone marrow harvests were rescued after processing and transfused as the sole transfusion support after surgery. There was no correlation between volume of harvest and total mononuclear cell (MNC) count. The marrow collection induced a significant decrease in hematocrit values (mean, 6.1; range, -0.3-12.3; p<0.001) unrelated to the patient's diagnosis, age, or gender. Processing of the marrows resulted in a mean transfused MRBC mass of 258 mL (range, 101-494 mL), representing 78 percent (range, 43-100%) of the MRBC mass collected. The amount of MRBCs transfused correlated with total MNC count (p<0.01). All autologous MRBC transfusions were well tolerated. It can be concluded that autologous MRBC transfusions are safe and may eliminate the need for homologous blood transfusions after marrow harvest.

Original languageEnglish (US)
Pages (from-to)231-234
Number of pages4
JournalTransfusion
Volume32
Issue number3
StatePublished - 1992

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Bone Marrow
Cell Count
Hematocrit
Blood Transfusion

ASJC Scopus subject areas

  • Immunology
  • Hematology

Cite this

Ciobanu, N., Weinberg, V., Sparano, J. A., Zervos, G., Walewski, J., Spivack, M., & Wiernik, P. H. (1992). Experience with autologous bone marrow harvesting and transfusion of marrow-derived red cells. Transfusion, 32(3), 231-234.

Experience with autologous bone marrow harvesting and transfusion of marrow-derived red cells. / Ciobanu, N.; Weinberg, V.; Sparano, Joseph A.; Zervos, G.; Walewski, J.; Spivack, M.; Wiernik, P. H.

In: Transfusion, Vol. 32, No. 3, 1992, p. 231-234.

Research output: Contribution to journalArticle

Ciobanu, N, Weinberg, V, Sparano, JA, Zervos, G, Walewski, J, Spivack, M & Wiernik, PH 1992, 'Experience with autologous bone marrow harvesting and transfusion of marrow-derived red cells', Transfusion, vol. 32, no. 3, pp. 231-234.
Ciobanu N, Weinberg V, Sparano JA, Zervos G, Walewski J, Spivack M et al. Experience with autologous bone marrow harvesting and transfusion of marrow-derived red cells. Transfusion. 1992;32(3):231-234.
Ciobanu, N. ; Weinberg, V. ; Sparano, Joseph A. ; Zervos, G. ; Walewski, J. ; Spivack, M. ; Wiernik, P. H. / Experience with autologous bone marrow harvesting and transfusion of marrow-derived red cells. In: Transfusion. 1992 ; Vol. 32, No. 3. pp. 231-234.
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AU - Weinberg, V.

AU - Sparano, Joseph A.

AU - Zervos, G.

AU - Walewski, J.

AU - Spivack, M.

AU - Wiernik, P. H.

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