Experience with a modified composite sequential bypass technique for limb-threatening ischemia

Nicholas J. Gargiulo, Frank J. Veith, David J. O'Connor, Evan C. Lipsitz, William D. Suggs, Larry A. Scher

Research output: Contribution to journalArticle

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Abstract

Background: Composite sequential femoro-popliteal-distal bypass is a valuable option for treatment of critical limb ischemia when autogenous vein is limited and an isolated popliteal or distal arterial segment exists. We report a modified technique for composite sequential bypass and the results with its use over a 14-year period. Methods: Twenty-five modified composite sequential bypass procedures were performed on 24 patients to treat gangrene, ischemic ulceration, and severe rest pain. Vein grafts were anastomosed from blind popliteal or blind distal arterial segments above-knee (7) or below-knee (18) to a distal outflow vessel including the below-knee popliteal (1), posterior tibial (5), anterior tibial (7), or peroneal (12) artery. Polytetrafluoroethylene bypass grafts were then placed from a suitable inflow artery to the proximal hood of the vein graft. Results: Cumulative primary patency rates were 80% at 3 years, and 65% at 5 years. The limb-salvage rate was 85% at 4 years. Occlusion of the prosthetic segment with a patent distal vein segment was recognized in two patients who presented with less severe recurrent ischemia. Limb-salvage in these patients was achieved by a secondary prosthetic graft to the patent vein graft. Conclusion: Our modified configuration of the prosthetic-vein anastomosis for composite sequential bypass is an alternative to the conventional procedure and may help preserve vein graft patency should the polytetrafluoroethylene graft thrombose.

Original languageEnglish (US)
Pages (from-to)1000-1004
Number of pages5
JournalAnnals of Vascular Surgery
Volume24
Issue number8
DOIs
StatePublished - Nov 2010

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Veins
Ischemia
Extremities
Transplants
Knee
Limb Salvage
Polytetrafluoroethylene
Arteries
Gangrene
Thrombosis
Pain

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Experience with a modified composite sequential bypass technique for limb-threatening ischemia. / Gargiulo, Nicholas J.; Veith, Frank J.; O'Connor, David J.; Lipsitz, Evan C.; Suggs, William D.; Scher, Larry A.

In: Annals of Vascular Surgery, Vol. 24, No. 8, 11.2010, p. 1000-1004.

Research output: Contribution to journalArticle

Gargiulo, Nicholas J. ; Veith, Frank J. ; O'Connor, David J. ; Lipsitz, Evan C. ; Suggs, William D. ; Scher, Larry A. / Experience with a modified composite sequential bypass technique for limb-threatening ischemia. In: Annals of Vascular Surgery. 2010 ; Vol. 24, No. 8. pp. 1000-1004.
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