Evolving management of newly diagnosed brain metastases: Expanding role of radiosurgery in lieu of whole brain radiation

Jana Fox, Lawrence Kleinberg

Research output: Contribution to journalArticle


The use of stereotactic radiosurgery has grown increasingly prevalent in the management of patients with brain metastases. In this perspective we contend that a large number of patients can be offered the alternative of treatment with this modality alone, reserving whole brain radiation for salvage. The relevant data will be presented supporting this approach, with emphasis on the toxicities of whole brain radiation and equivalence of survival outcomes regardless of treatment approach. Patient selection for radiosurgery alone will also be addressed.

Original languageEnglish (US)
Pages (from-to)285-293
Number of pages9
JournalFuture Oncology
Issue number3
Publication statusPublished - Jun 1 2007
Externally publishedYes



  • Brain metastases
  • Radiosurgery
  • Recurrence
  • Salvage
  • Stereotactic
  • Survival
  • WBRT
  • Whole brain radiation

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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