Evidence against insulin synthesis by IM-9 lymphocytes

W. A. Bauman, V. B. Hatcher, M. A. Levitt, R. S. Yalow

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Insulin concentrated from acid/ethanol extracts of IM-9 lymphocytes by the use of octadecylsilyl (ODS) silica cartridges averaged 0.13 ng/ml cell volume compared with the 0.12 ng insulin/ml cell culture medium. The insulin content of these cells appears to be less than 1% of previously reported values and probably could be accounted for by concentration of insulin from the incubation medium on cell receptors.

Original languageEnglish (US)
Pages (from-to)182-184
Number of pages3
JournalDiabetes
Volume31
Issue number2
DOIs
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

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