Evaluation of a multi-scale enhancement protocol for digital mammography

Ralf Mekle, Andrew Laine, Suzanne Smith, Cory Singer, Tova C. Koenigsberg, Marc Brown

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Abstract

We have carried out a receiver operating characteristics (ROC) study for the enhancement of mammographic features in digitized mammograms. The study evaluated the benefits of multi-scale enhancement methods in terms of diagnostic performance of radiologists. The enhancement protocol relied on multi-scale expansions and non-linear enhancement functions. Dyadic spline wavelet functions (first derivative of a cubic spline) were used together with a sigmoidal non-linear enhancement function. We designed a computer interface on a softcopy display and performed an ROC study with three radiologists, who specialized in mammography. Clinical cases were obtained from a national mammography database of digitized radiographs prepared by the University of South Florida (USF) and Harvard Medical School. Our study focused on dense mammograms, i.e. mammograms of density 3 and 4 on the American College of Radiology (ACR) breast density rating, which are the most difficult cases in screening, were selected. To compare the performance of radiologists with and without using multi-scale enhancement, two groups of 30 cases each were diagnosed. Each group contained 15 cases of cancerous and 15 cases of normal mammograms. Conventional ROC analysis was applied, and the resulting ROC curves indicated improved diagnostic performance when radiologists used multi-scale non-linear enhancement.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
Pages1038-1049
Number of pages12
Volume4119
DOIs
StatePublished - 2000
Externally publishedYes
EventWavelet Applications in Signal and Image Processing VIII - San Diego, CA, USA
Duration: Jul 31 2000Aug 4 2000

Other

OtherWavelet Applications in Signal and Image Processing VIII
CitySan Diego, CA, USA
Period7/31/008/4/00

Fingerprint

Mammography
Network protocols
Splines
augmentation
evaluation
receivers
Radiology
splines
Interfaces (computer)
Screening
Display devices
Derivatives
dyadics
radiology
ratings
breast
screening
expansion
curves

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Mekle, R., Laine, A., Smith, S., Singer, C., Koenigsberg, T. C., & Brown, M. (2000). Evaluation of a multi-scale enhancement protocol for digital mammography. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4119, pp. 1038-1049) https://doi.org/10.1117/12.408591

Evaluation of a multi-scale enhancement protocol for digital mammography. / Mekle, Ralf; Laine, Andrew; Smith, Suzanne; Singer, Cory; Koenigsberg, Tova C.; Brown, Marc.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4119 2000. p. 1038-1049.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mekle, R, Laine, A, Smith, S, Singer, C, Koenigsberg, TC & Brown, M 2000, Evaluation of a multi-scale enhancement protocol for digital mammography. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 4119, pp. 1038-1049, Wavelet Applications in Signal and Image Processing VIII, San Diego, CA, USA, 7/31/00. https://doi.org/10.1117/12.408591
Mekle R, Laine A, Smith S, Singer C, Koenigsberg TC, Brown M. Evaluation of a multi-scale enhancement protocol for digital mammography. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4119. 2000. p. 1038-1049 https://doi.org/10.1117/12.408591
Mekle, Ralf ; Laine, Andrew ; Smith, Suzanne ; Singer, Cory ; Koenigsberg, Tova C. ; Brown, Marc. / Evaluation of a multi-scale enhancement protocol for digital mammography. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4119 2000. pp. 1038-1049
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