Estrogen Replacement Therapy in Breast Cancer Survivors

A Time for Change

Melody A. Cobleigh, Robert F. Berris, Trudy Bush, Nancy E. Davidson, Nicholas J. Robert, Joseph A. Sparano, Douglas C. Tormey, William C. Wood

Research output: Contribution to journalArticle

149 Citations (Scopus)

Abstract

POSTMENOPAUSAL women often experience annoying and sometimes debilitating menopausal symptoms, and breast cancer survivors are no exception. Hot flashes, dyspareunia, atrophic vaginitis with attendant urinary tract symptoms, sleep disturbance, and mood change are among these symptoms. Coronary artery disease and osteoporosis may be more insidious, but potentially fatal consequences of menopausal estrogen decline. Estrogen replacement therapy (ERT) has been shown to ameliorate these problems,1,2 and as informed consumers, breast cancer survivors are increasingly inquiring about and/or requesting ERT.3 There are more breast cancer survivors alive now than ever before, so their nononcologic health problems are a growing concern. A dramatic rise in the incidence rates of breast cancer occurred in the United States between 1982 and 1987, presumably because of increased screening.4 The incidence of noninvasive and of small, invasive, axillary nodenegative breast cancers rose concurrently.4 Five-year survival rates for breast cancer patients also have been.

Original languageEnglish (US)
Pages (from-to)540-545
Number of pages6
JournalJAMA - Journal of the American Medical Association
Volume272
Issue number7
DOIs
StatePublished - 1994
Externally publishedYes

Fingerprint

Estrogen Replacement Therapy
Survivors
Breast Neoplasms
Atrophic Vaginitis
Hot Flashes
Dyspareunia
Incidence
Urinary Tract
Osteoporosis
Coronary Artery Disease
Sleep
Estrogens
Survival Rate
Health

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Estrogen Replacement Therapy in Breast Cancer Survivors : A Time for Change. / Cobleigh, Melody A.; Berris, Robert F.; Bush, Trudy; Davidson, Nancy E.; Robert, Nicholas J.; Sparano, Joseph A.; Tormey, Douglas C.; Wood, William C.

In: JAMA - Journal of the American Medical Association, Vol. 272, No. 7, 1994, p. 540-545.

Research output: Contribution to journalArticle

Cobleigh, MA, Berris, RF, Bush, T, Davidson, NE, Robert, NJ, Sparano, JA, Tormey, DC & Wood, WC 1994, 'Estrogen Replacement Therapy in Breast Cancer Survivors: A Time for Change', JAMA - Journal of the American Medical Association, vol. 272, no. 7, pp. 540-545. https://doi.org/10.1001/jama.1994.03520070060039
Cobleigh, Melody A. ; Berris, Robert F. ; Bush, Trudy ; Davidson, Nancy E. ; Robert, Nicholas J. ; Sparano, Joseph A. ; Tormey, Douglas C. ; Wood, William C. / Estrogen Replacement Therapy in Breast Cancer Survivors : A Time for Change. In: JAMA - Journal of the American Medical Association. 1994 ; Vol. 272, No. 7. pp. 540-545.
@article{8c9d5c5ad9404930815e72bb4a5c23cc,
title = "Estrogen Replacement Therapy in Breast Cancer Survivors: A Time for Change",
abstract = "POSTMENOPAUSAL women often experience annoying and sometimes debilitating menopausal symptoms, and breast cancer survivors are no exception. Hot flashes, dyspareunia, atrophic vaginitis with attendant urinary tract symptoms, sleep disturbance, and mood change are among these symptoms. Coronary artery disease and osteoporosis may be more insidious, but potentially fatal consequences of menopausal estrogen decline. Estrogen replacement therapy (ERT) has been shown to ameliorate these problems,1,2 and as informed consumers, breast cancer survivors are increasingly inquiring about and/or requesting ERT.3 There are more breast cancer survivors alive now than ever before, so their nononcologic health problems are a growing concern. A dramatic rise in the incidence rates of breast cancer occurred in the United States between 1982 and 1987, presumably because of increased screening.4 The incidence of noninvasive and of small, invasive, axillary nodenegative breast cancers rose concurrently.4 Five-year survival rates for breast cancer patients also have been.",
author = "Cobleigh, {Melody A.} and Berris, {Robert F.} and Trudy Bush and Davidson, {Nancy E.} and Robert, {Nicholas J.} and Sparano, {Joseph A.} and Tormey, {Douglas C.} and Wood, {William C.}",
year = "1994",
doi = "10.1001/jama.1994.03520070060039",
language = "English (US)",
volume = "272",
pages = "540--545",
journal = "JAMA - Journal of the American Medical Association",
issn = "0002-9955",
publisher = "American Medical Association",
number = "7",

}

TY - JOUR

T1 - Estrogen Replacement Therapy in Breast Cancer Survivors

T2 - A Time for Change

AU - Cobleigh, Melody A.

AU - Berris, Robert F.

AU - Bush, Trudy

AU - Davidson, Nancy E.

AU - Robert, Nicholas J.

AU - Sparano, Joseph A.

AU - Tormey, Douglas C.

AU - Wood, William C.

PY - 1994

Y1 - 1994

N2 - POSTMENOPAUSAL women often experience annoying and sometimes debilitating menopausal symptoms, and breast cancer survivors are no exception. Hot flashes, dyspareunia, atrophic vaginitis with attendant urinary tract symptoms, sleep disturbance, and mood change are among these symptoms. Coronary artery disease and osteoporosis may be more insidious, but potentially fatal consequences of menopausal estrogen decline. Estrogen replacement therapy (ERT) has been shown to ameliorate these problems,1,2 and as informed consumers, breast cancer survivors are increasingly inquiring about and/or requesting ERT.3 There are more breast cancer survivors alive now than ever before, so their nononcologic health problems are a growing concern. A dramatic rise in the incidence rates of breast cancer occurred in the United States between 1982 and 1987, presumably because of increased screening.4 The incidence of noninvasive and of small, invasive, axillary nodenegative breast cancers rose concurrently.4 Five-year survival rates for breast cancer patients also have been.

AB - POSTMENOPAUSAL women often experience annoying and sometimes debilitating menopausal symptoms, and breast cancer survivors are no exception. Hot flashes, dyspareunia, atrophic vaginitis with attendant urinary tract symptoms, sleep disturbance, and mood change are among these symptoms. Coronary artery disease and osteoporosis may be more insidious, but potentially fatal consequences of menopausal estrogen decline. Estrogen replacement therapy (ERT) has been shown to ameliorate these problems,1,2 and as informed consumers, breast cancer survivors are increasingly inquiring about and/or requesting ERT.3 There are more breast cancer survivors alive now than ever before, so their nononcologic health problems are a growing concern. A dramatic rise in the incidence rates of breast cancer occurred in the United States between 1982 and 1987, presumably because of increased screening.4 The incidence of noninvasive and of small, invasive, axillary nodenegative breast cancers rose concurrently.4 Five-year survival rates for breast cancer patients also have been.

UR - http://www.scopus.com/inward/record.url?scp=84942384277&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84942384277&partnerID=8YFLogxK

U2 - 10.1001/jama.1994.03520070060039

DO - 10.1001/jama.1994.03520070060039

M3 - Article

VL - 272

SP - 540

EP - 545

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

SN - 0002-9955

IS - 7

ER -