Thomas J. Ow, Diana Bell, Michael E. Kupferman, Franco DeMonte, Ehab Y. Hanna

Research output: Contribution to journalReview articlepeer-review

73 Scopus citations


Esthesioneuroblastoma is a rare malignant neoplasm in the olfactory region of the nasal cavity and anterior skull base. Diagnosis and staging require anatomic imaging and careful pathologic assessment. Standard treatment is anterior craniofacial resection with postoperative irradiation. The role for chemotherapy is not defined, but is generally for the most advanced cases and used in the neoadjuvant setting and/or postoperatively with irradiation. Prognosis is favorable; however, metastasis rates remain relatively high. Regional and distant metastasis portends a poor outcome. Intensity-modulated radiation treatment and endoscopic surgery have reduced morbidity, but outcomes with these techniques must be fully evaluated.

Original languageEnglish (US)
Pages (from-to)51-65
Number of pages15
JournalNeurosurgery clinics of North America
Issue number1
StatePublished - Jan 2013
Externally publishedYes


  • Endoscopic resection
  • Esthesioneuroblastoma
  • Multimodality treatment

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


Dive into the research topics of 'Esthesioneuroblastoma'. Together they form a unique fingerprint.

Cite this