Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis

A new twist on an old tale

Madhav C. Menon, Michael J. Ross

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.

Original languageEnglish (US)
Pages (from-to)263-266
Number of pages4
JournalKidney International
Volume89
Issue number2
DOIs
StatePublished - Feb 1 2016
Externally publishedYes

Fingerprint

Epithelial-Mesenchymal Transition
Fibrosis
Epithelial Cells
Cell Dedifferentiation
Kidney
Myofibroblasts
Wounds and Injuries

ASJC Scopus subject areas

  • Medicine(all)
  • Nephrology

Cite this

Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis : A new twist on an old tale. / Menon, Madhav C.; Ross, Michael J.

In: Kidney International, Vol. 89, No. 2, 01.02.2016, p. 263-266.

Research output: Contribution to journalArticle

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