Abstract
Objectives: Ethmoid punch sinusotomy (EPS) is a feasible treatment for ethmoid sinusitis in a subset of chronic rhinosinusitis (CRS) patients per a recent report. This adjunctive work investigates the technical characteristics of EPS and determines if EPS measurably alters the topical delivery of irrigant into the ethmoid sinuses in a cadaveric model. Methods: The sinonasal cavities of 10 human cadaver heads were irrigated with a solution containing methylene blue and radio-opaque contrast prior to and following EPS. Procedural characteristics and irrigant distribution were assessed by endoscopy and computed tomography. Results: Forty EPS procedures were performed through the ethmoid bulla and basal lamella. Compared to controls, EPS enhanced dye distribution into the anterior (90% vs 35%, P <.004) and posterior (90% vs 35%, P <.002) ethmoid sinuses, representing a 157% increase for each of these sites. Contrast was detected in a higher proportion of anterior (65% vs 5%, P <.001) and posterior (60% vs 0%, P <.001) ethmoid sinuses. Endoscopically guided catheter instillation of contrast through the EPS sites achieved radiotracer distribution throughout the ethmoid complex. Conclusions: Ethmoid punch sinusotomy sites can be reliably created via micro-minimally invasive procedures. Ethmoid punch sinusotomy improves irrigant delivery to the ethmoid sinuses, providing mechanistic understanding for the clinical outcomes observed in CRS patients.
Original language | English (US) |
---|---|
Pages (from-to) | 804-812 |
Number of pages | 9 |
Journal | Annals of Otology, Rhinology and Laryngology |
Volume | 126 |
Issue number | 12 |
DOIs | |
State | Published - Dec 1 2017 |
Keywords
- CRS
- balloon catheter dilation
- balloon sinuplasty
- chronic rhinosinusitis
- drug delivery
- ethmoid sinusitis
- minimally invasive surgical procedures
- sinus ventilation
- topical drug administration
ASJC Scopus subject areas
- Otorhinolaryngology