Enflurane hepatitis

Robert J. Masone, Joel P. Goldfarb, Nancy C. Manzione, L. Biempica

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Abstract

Enflurane (ethrane; 2-chloro-1,2,2-trifluoroethyl difluoromethyl ether) has been widely used as an alternative general anesthetic agent to halothane over the past decade because halothane has been directly linked to hepatocellular damage. Several case reports have subsequently described a hepatitis after exposure to enflurane. We describe another case of enflurane hepatitis which supports earlier reports of this entity, discuss possible mechanisms of such hepatocellular damage, and review the pertinent literature.

Original languageEnglish (US)
Pages (from-to)541-545
Number of pages5
JournalJournal of clinical gastroenterology
Volume4
Issue number6
DOIs
Publication statusPublished - Dec 1982

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ASJC Scopus subject areas

  • Gastroenterology

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