Enflurane hepatitis

Robert J. Masone; Joel P. Goldfarb; Nancy C. Manzione; L. Biempica

doi:10.1097/00004836-198212000-00012

Enflurane hepatitis

Robert J. Masone, Joel P. Goldfarb, Nancy C. Manzione, L. Biempica

Medicine

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3 Scopus citations

Abstract

Enflurane (ethrane; 2-chloro-1,2,2-trifluoroethyl difluoromethyl ether) has been widely used as an alternative general anesthetic agent to halothane over the past decade because halothane has been directly linked to hepatocellular damage. Several case reports have subsequently described a hepatitis after exposure to enflurane. We describe another case of enflurane hepatitis which supports earlier reports of this entity, discuss possible mechanisms of such hepatocellular damage, and review the pertinent literature.

Original language	English (US)
Pages (from-to)	541-545
Number of pages	5
Journal	Journal of clinical gastroenterology
Volume	4
Issue number	6
DOIs	https://doi.org/10.1097/00004836-198212000-00012
State	Published - Dec 1982

ASJC Scopus subject areas

Gastroenterology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/00004836-198212000-00012

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title = "Enflurane hepatitis",

abstract = "Enflurane (ethrane; 2-chloro-1,2,2-trifluoroethyl difluoromethyl ether) has been widely used as an alternative general anesthetic agent to halothane over the past decade because halothane has been directly linked to hepatocellular damage. Several case reports have subsequently described a hepatitis after exposure to enflurane. We describe another case of enflurane hepatitis which supports earlier reports of this entity, discuss possible mechanisms of such hepatocellular damage, and review the pertinent literature.",

author = "Masone, {Robert J.} and Goldfarb, {Joel P.} and Manzione, {Nancy C.} and L. Biempica",

year = "1982",

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language = "English (US)",

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TY - JOUR

T1 - Enflurane hepatitis

AU - Masone, Robert J.

AU - Goldfarb, Joel P.

AU - Manzione, Nancy C.

AU - Biempica, L.

PY - 1982/12

Y1 - 1982/12

N2 - Enflurane (ethrane; 2-chloro-1,2,2-trifluoroethyl difluoromethyl ether) has been widely used as an alternative general anesthetic agent to halothane over the past decade because halothane has been directly linked to hepatocellular damage. Several case reports have subsequently described a hepatitis after exposure to enflurane. We describe another case of enflurane hepatitis which supports earlier reports of this entity, discuss possible mechanisms of such hepatocellular damage, and review the pertinent literature.

AB - Enflurane (ethrane; 2-chloro-1,2,2-trifluoroethyl difluoromethyl ether) has been widely used as an alternative general anesthetic agent to halothane over the past decade because halothane has been directly linked to hepatocellular damage. Several case reports have subsequently described a hepatitis after exposure to enflurane. We describe another case of enflurane hepatitis which supports earlier reports of this entity, discuss possible mechanisms of such hepatocellular damage, and review the pertinent literature.

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JF - Journal of clinical gastroenterology

IS - 6

ER -

Enflurane hepatitis

Abstract

ASJC Scopus subject areas

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