Endothelial apoptosis: Could it have a role in the pathogenesis and treatment of disease?

Research output: Contribution to journalReview article

150 Scopus citations

Abstract

Endothelial apoptosis can be found in a number of diseases. This review summarizes the current knowledge about the causes and consequences of endothelial apoptosis, and analyzes its possible role in the pathogenesis and treatment of several diseases. Novel forms of therapy based on the proposed pathophysiologic mechanisms are discussed.

Original languageEnglish (US)
Pages (from-to)841-854
Number of pages14
JournalChest
Volume117
Issue number3
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

Keywords

  • Apoptosis
  • Atherosclerosis
  • Endothelium
  • Heart failure
  • Hypertension
  • Primary pulmonary hypertension
  • Sepsis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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