Efficacy of combined technetium-99m sulfur colloid/indium-111 leukocyte scans to detect infected total hip and knee arthroplasties

Thomas N. Joseph, Mohammed Mujtaba, Andrew L. Chen, Stephen L. Maurer, Joseph D. Zuckerman, Catherine Maldjian, Paul E. Di Cesare

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

The reliability of combined indium-111 leukocyte/technetium-99m sulfur colloid scans, with and without the addition of blood pooling and blood flow studies, in the diagnosis of infected total joint arthroplasty was investigated. Both scans were performed on 58 patients before reoperation of total hip or knee arthroplasty in the period 1996-1999. Results for imaging alone included 100% specificity, 46% sensitivity, 100% positive predictive value, 84% negative predictive value, and 88% accuracy. Inclusion of blood pooling and flow phase data improved results to 66% sensitivity, 89% negative predictive value, and 90% accuracy, with reductions in specificity (98%) and positive predictive value (91%). Routine use of these radionuclide scans is not supported by these data.

Original languageEnglish (US)
Pages (from-to)753-758
Number of pages6
JournalJournal of Arthroplasty
Volume16
Issue number6
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • Indium scan
  • Infection
  • Revision
  • Sulfur colloid scan
  • Total joint arthroplasty

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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