TY - JOUR
T1 - Effects of depressive symptoms and mental health quality of life on use of highly active antiretroviral therapy among HIV-seropositive women
AU - Cook, Judith A.
AU - Cohen, Mardge H.
AU - Burke, Jane
AU - Grey, Dennis
AU - Anastos, Kathryn
AU - Kirstein, Lynn
AU - Palacio, Herminia
AU - Richardson, Jean
AU - Wilson, Tracey
AU - Young, Mary
PY - 2002/8/1
Y1 - 2002/8/1
N2 - This study examines the effects of depressive symptoms and mental health quality of life on utilization of highly active antiretroviral therapy (HAART) among HIV-seropositive women. Data were collected biannually from 1996 through 1998 in a prospective cohort study. Women reported use of antiretroviral therapy, health and mental health status, demographics, and social and behavioral factors; CD4 count and viral load also were assessed. Random effects regression models estimated the longitudinal effects of depressive symptoms and mental health quality of life on the probability of HAART utilization, controlling for clinical indicators (CD4 count, viral load, symptom presence), demographics (race, age, education), behavioral factors (drug/alcohol use, clinical trials participation), service features (insurance status, mental health service utilization), and study site. High levels of depressive symptoms and poor mental health quality of life were found, and they significantly reduced the probability of HAART utilization. Receiving mental health services significantly increased the probability of utilizing HAART. HIV-seropositive women characterized as being in poor mental health were less likely to use HAART, whereas those receiving treatment of mental health difficulties were more likely to use HAART. These findings suggest that efforts to enhance women's access to psychological treatment may increase their use of the latest HIV therapies.
AB - This study examines the effects of depressive symptoms and mental health quality of life on utilization of highly active antiretroviral therapy (HAART) among HIV-seropositive women. Data were collected biannually from 1996 through 1998 in a prospective cohort study. Women reported use of antiretroviral therapy, health and mental health status, demographics, and social and behavioral factors; CD4 count and viral load also were assessed. Random effects regression models estimated the longitudinal effects of depressive symptoms and mental health quality of life on the probability of HAART utilization, controlling for clinical indicators (CD4 count, viral load, symptom presence), demographics (race, age, education), behavioral factors (drug/alcohol use, clinical trials participation), service features (insurance status, mental health service utilization), and study site. High levels of depressive symptoms and poor mental health quality of life were found, and they significantly reduced the probability of HAART utilization. Receiving mental health services significantly increased the probability of utilizing HAART. HIV-seropositive women characterized as being in poor mental health were less likely to use HAART, whereas those receiving treatment of mental health difficulties were more likely to use HAART. These findings suggest that efforts to enhance women's access to psychological treatment may increase their use of the latest HIV therapies.
KW - Depression
KW - HAART utilization
KW - HIV-seropositive women
KW - Mental health
UR - http://www.scopus.com/inward/record.url?scp=0036683084&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036683084&partnerID=8YFLogxK
U2 - 10.1097/00042560-200208010-00005
DO - 10.1097/00042560-200208010-00005
M3 - Article
C2 - 12138346
AN - SCOPUS:0036683084
SN - 1525-4135
VL - 30
SP - 401
EP - 409
JO - Journal of Acquired Immune Deficiency Syndromes
JF - Journal of Acquired Immune Deficiency Syndromes
IS - 4
ER -