Effects of depressive symptoms and mental health quality of life on use of highly active antiretroviral therapy among HIV-seropositive women

Judith A. Cook, Mardge H. Cohen, Jane Burke, Dennis Grey, Kathryn Anastos, Lynn Kirstein, Herminia Palacio, Jean Richardson, Tracey Wilson, Mary Young

Research output: Contribution to journalArticle

152 Citations (Scopus)

Abstract

This study examines the effects of depressive symptoms and mental health quality of life on utilization of highly active antiretroviral therapy (HAART) among HIV-seropositive women. Data were collected biannually from 1996 through 1998 in a prospective cohort study. Women reported use of antiretroviral therapy, health and mental health status, demographics, and social and behavioral factors; CD4 count and viral load also were assessed. Random effects regression models estimated the longitudinal effects of depressive symptoms and mental health quality of life on the probability of HAART utilization, controlling for clinical indicators (CD4 count, viral load, symptom presence), demographics (race, age, education), behavioral factors (drug/alcohol use, clinical trials participation), service features (insurance status, mental health service utilization), and study site. High levels of depressive symptoms and poor mental health quality of life were found, and they significantly reduced the probability of HAART utilization. Receiving mental health services significantly increased the probability of utilizing HAART. HIV-seropositive women characterized as being in poor mental health were less likely to use HAART, whereas those receiving treatment of mental health difficulties were more likely to use HAART. These findings suggest that efforts to enhance women's access to psychological treatment may increase their use of the latest HIV therapies.

Original languageEnglish (US)
Pages (from-to)401-409
Number of pages9
JournalJournal of Acquired Immune Deficiency Syndromes
Volume30
Issue number4
StatePublished - Aug 1 2002
Externally publishedYes

Fingerprint

Highly Active Antiretroviral Therapy
Mental Health
Quality of Life
HIV
Depression
Mental Health Services
CD4 Lymphocyte Count
Viral Load
Demography
Insurance Coverage
Therapeutics
Health Status
Cohort Studies
Alcohols
Clinical Trials
Prospective Studies
Psychology
Education
Health
Pharmaceutical Preparations

Keywords

  • Depression
  • HAART utilization
  • HIV-seropositive women
  • Mental health

ASJC Scopus subject areas

  • Virology
  • Immunology

Cite this

Effects of depressive symptoms and mental health quality of life on use of highly active antiretroviral therapy among HIV-seropositive women. / Cook, Judith A.; Cohen, Mardge H.; Burke, Jane; Grey, Dennis; Anastos, Kathryn; Kirstein, Lynn; Palacio, Herminia; Richardson, Jean; Wilson, Tracey; Young, Mary.

In: Journal of Acquired Immune Deficiency Syndromes, Vol. 30, No. 4, 01.08.2002, p. 401-409.

Research output: Contribution to journalArticle

Cook, JA, Cohen, MH, Burke, J, Grey, D, Anastos, K, Kirstein, L, Palacio, H, Richardson, J, Wilson, T & Young, M 2002, 'Effects of depressive symptoms and mental health quality of life on use of highly active antiretroviral therapy among HIV-seropositive women', Journal of Acquired Immune Deficiency Syndromes, vol. 30, no. 4, pp. 401-409.
Cook, Judith A. ; Cohen, Mardge H. ; Burke, Jane ; Grey, Dennis ; Anastos, Kathryn ; Kirstein, Lynn ; Palacio, Herminia ; Richardson, Jean ; Wilson, Tracey ; Young, Mary. / Effects of depressive symptoms and mental health quality of life on use of highly active antiretroviral therapy among HIV-seropositive women. In: Journal of Acquired Immune Deficiency Syndromes. 2002 ; Vol. 30, No. 4. pp. 401-409.
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