Effects of age, menopause, and comorbidities on neurological function of the female genitalia

K. Connell, M. K. Guess, C. B. Bleustein, K. Powers, G. Lazarou, M. Mikhail, A. Melman

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The aim of this study was to investigate the effects of age, menopause, and comorbidities on neurological function of the female genitalia using a noninvasive, validated technique. In all, 58 consecutive women were enrolled in the study. Biothesiometry was performed at five genital sites and one peripheral site with S2 dermatome distribution. Kruskal-Wallis one-way ANOVA on ranks was used to evaluate the relationship between age and vibratory sensation. Bivariate and regressional analyses were performed to evaluate the effects of age, menopause and comorbidities on genital sensation. The mean age was 44.6 + 14.8 y (range 20-78 y). Vibration thresholds increased with advancing age at all six sites. Multilinear regression analysis indicated that menopause and increasing age negatively affect sensation. History of herniated lumbar disc, vaginal delivery, and diabetes variably affected genital sensation. There is a significant increase in vibration thresholds (indicating worsening neurological function) in women as they age and undergo menopause. Biothesiometry is a technique for evaluating genital neurological function in women with coexisting morbidities.

Original languageEnglish (US)
Pages (from-to)63-70
Number of pages8
JournalInternational Journal of Impotence Research
Volume17
Issue number1
DOIs
StatePublished - Jan 2005

Fingerprint

Female Genitalia
Menopause
Comorbidity
Vibration
Intervertebral Disc Displacement
Analysis of Variance
Regression Analysis
Morbidity

Keywords

  • Aging
  • Female genital sensation
  • Menopause
  • Quantitative sensory testing

ASJC Scopus subject areas

  • Urology

Cite this

Connell, K., Guess, M. K., Bleustein, C. B., Powers, K., Lazarou, G., Mikhail, M., & Melman, A. (2005). Effects of age, menopause, and comorbidities on neurological function of the female genitalia. International Journal of Impotence Research, 17(1), 63-70. https://doi.org/10.1038/sj.ijir.3901230

Effects of age, menopause, and comorbidities on neurological function of the female genitalia. / Connell, K.; Guess, M. K.; Bleustein, C. B.; Powers, K.; Lazarou, G.; Mikhail, M.; Melman, A.

In: International Journal of Impotence Research, Vol. 17, No. 1, 01.2005, p. 63-70.

Research output: Contribution to journalArticle

Connell, K, Guess, MK, Bleustein, CB, Powers, K, Lazarou, G, Mikhail, M & Melman, A 2005, 'Effects of age, menopause, and comorbidities on neurological function of the female genitalia', International Journal of Impotence Research, vol. 17, no. 1, pp. 63-70. https://doi.org/10.1038/sj.ijir.3901230
Connell, K. ; Guess, M. K. ; Bleustein, C. B. ; Powers, K. ; Lazarou, G. ; Mikhail, M. ; Melman, A. / Effects of age, menopause, and comorbidities on neurological function of the female genitalia. In: International Journal of Impotence Research. 2005 ; Vol. 17, No. 1. pp. 63-70.
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