Effect of sodium cyanate on trypanosoma cruzi in culture

Jeffrey P. Nadler; Herbert B. Tanowitz; Carmen Raventos; Ronald L. Nagel; Murray Wittner

doi:10.1016/0035-9203(81)90158-9

Effect of sodium cyanate on trypanosoma cruzi in culture

Jeffrey P. Nadler, Herbert B. Tanowitz, Carmen Raventos, Ronald L. Nagel, Murray Wittner

Pathology

Research output: Contribution to journal › Article › peer-review

Abstract

The Brazil strain of Trypanosoma cruzi was shown in vitro to be sensitive to the carbamylating agent NaNCO in a dose and time-dependent fashion. The organisms may be irreversibly inhibited by high doses of NaNCO. It was not found to be effective in vivo in acutely infected mice.

Original language	English (US)
Pages (from-to)	710-712
Number of pages	3
Journal	Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume	75
Issue number	5
DOIs	https://doi.org/10.1016/0035-9203(81)90158-9
State	Published - 1981

ASJC Scopus subject areas

Parasitology
Public Health, Environmental and Occupational Health
Infectious Diseases

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title = "Effect of sodium cyanate on trypanosoma cruzi in culture",

abstract = "The Brazil strain of Trypanosoma cruzi was shown in vitro to be sensitive to the carbamylating agent NaNCO in a dose and time-dependent fashion. The organisms may be irreversibly inhibited by high doses of NaNCO. It was not found to be effective in vivo in acutely infected mice.",

author = "Nadler, {Jeffrey P.} and Tanowitz, {Herbert B.} and Carmen Raventos and Nagel, {Ronald L.} and Murray Wittner",

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AU - Wittner, Murray

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AB - The Brazil strain of Trypanosoma cruzi was shown in vitro to be sensitive to the carbamylating agent NaNCO in a dose and time-dependent fashion. The organisms may be irreversibly inhibited by high doses of NaNCO. It was not found to be effective in vivo in acutely infected mice.

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