Effect of dopamine beta hydroxylase inhibition on cerebral vasospasm in the cat

A. F. Battista; E. S. Flamm; M. Goldstein; L. S. Freedman

doi:10.3171/jns.1976.44.2.0168

Effect of dopamine beta hydroxylase inhibition on cerebral vasospasm in the cat

A. F. Battista, E. S. Flamm, M. Goldstein, L. S. Freedman

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Inhibitors of dopamine beta hydroxylase (DBH) administered intraperitoneally were shown to prevent spasm of the basilar artery caused by blood application in cats. A low or nondetectable blood DBH activity level may be related to the absence of spasm. In several instances, however, moderate spasm did occur with a low blood DBH activity level. Possible mechanisms for these findings are discussed.

Original language	English (US)
Pages (from-to)	168-172
Number of pages	5
Journal	Journal of neurosurgery
Volume	44
Issue number	2
DOIs	https://doi.org/10.3171/jns.1976.44.2.0168
State	Published - 1976
Externally published	Yes

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.3171/jns.1976.44.2.0168

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abstract = "Inhibitors of dopamine beta hydroxylase (DBH) administered intraperitoneally were shown to prevent spasm of the basilar artery caused by blood application in cats. A low or nondetectable blood DBH activity level may be related to the absence of spasm. In several instances, however, moderate spasm did occur with a low blood DBH activity level. Possible mechanisms for these findings are discussed.",

author = "Battista, {A. F.} and Flamm, {E. S.} and M. Goldstein and Freedman, {L. S.}",

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AU - Flamm, E. S.

AU - Goldstein, M.

AU - Freedman, L. S.

PY - 1976

Y1 - 1976

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AB - Inhibitors of dopamine beta hydroxylase (DBH) administered intraperitoneally were shown to prevent spasm of the basilar artery caused by blood application in cats. A low or nondetectable blood DBH activity level may be related to the absence of spasm. In several instances, however, moderate spasm did occur with a low blood DBH activity level. Possible mechanisms for these findings are discussed.

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ER -

Effect of dopamine beta hydroxylase inhibition on cerebral vasospasm in the cat

Abstract

ASJC Scopus subject areas

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