Effect of dopamine beta hydroxylase inhibition on cerebral vasospasm in the cat

A. F. Battista, E. S. Flamm, M. Goldstein, L. S. Freedman

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Inhibitors of dopamine beta hydroxylase (DBH) administered intraperitoneally were shown to prevent spasm of the basilar artery caused by blood application in cats. A low or nondetectable blood DBH activity level may be related to the absence of spasm. In several instances, however, moderate spasm did occur with a low blood DBH activity level. Possible mechanisms for these findings are discussed.

Original languageEnglish (US)
Pages (from-to)168-172
Number of pages5
JournalJournal of neurosurgery
Volume44
Issue number2
DOIs
StatePublished - Jan 1 1976
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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