Effect of direct suppression of thymidylate synthase at the 5,10-methylenetetrahydrofolate binding site on the interconversion of tetrahydrofolate cofactors to dihydrofolate by antifolates: Influence of degree of dihydrofolate reductase inhibition

R. L. Seither, D. F. Trent, D. C. Mikulecky, T. J. Rape, I. D. Goldman

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