Effect of coronary collaterals on limiting myocardial ischemia and infarct size

R. Charney, M. Cohen

Research output: Contribution to journalReview article

1 Scopus citations


Transluminal coronary angioplasty has provided a model to demonstrate that collaterals decrease wall motion abnormalities, ST-segment change, and lactate production during ischemia. During acute myocardial infarction (MI), the collateral circulation limits infarct size. Although collaterals may decrease coronary artery bypass graft patency in certain patient subgroups, the perioperative infarct rate and mortality are decreased. Growth factors have been identified that increase collateral development and may improve ventricular function in the setting of MI.

Original languageEnglish (US)
Pages (from-to)19-24
Number of pages6
JournalPrimary Cardiology
Issue number6
Publication statusPublished - Jan 1 1995
Externally publishedYes


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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