Effect of concomitant mitral valve procedures for severe mitral regurgitation during left ventricular assist device implantation

Masashi Kawabori, Chitaru Kurihara, Ryan T. Conyer, Andre C. Critsinelis, Tadahisa Sugiura, Todd Rosengart, Jeffrey A. Morgan

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The effect of performing a concomitant mitral valve procedure (MVP) during continuous-flow left ventricular assist device (CF-LVAD) implantation has been reported for patients with moderate-to-severe mitral regurgitation (MR), but moderate MR is less of a clinical concern for CF-LVAD patients. There is a paucity of reports focusing on patients with severe MR. Thus, the purpose of this study was to analyze the effect of performing a concomitant MVP during CF-LVAD implantation in patients with severe preoperative MR. Between November 2003 and March 2016, 526 patients underwent primary implantation of a CF-LVAD at our center. Patients with severe MR who underwent a concomitant MVP were compared to those who did not in regard to overall survival, perioperative complications, postoperative echocardiography data, bridge-to-transplantation success, and CF-LVAD explantation. Of the 108 patients with severe MR, 26 underwent a concomitant MVP and 82 did not. These groups showed no difference in survival (p = 0.61). Additionally, the two groups had similar rates of postoperative right heart failure (p = 0.69) and readmissions (p = 0.42). The 24-month follow-up echocardiography results were also similar. Furthermore, the groups showed no difference in bridge-to-cardiac transplantation success (30.0% vs 25.0%, p = 0.80) or CF-LVAD explantation rates (0.0% vs 0.0%. p = 1.0). Our findings suggest that patients with severe MR who undergo a MVP during CF-LVAD implantation do not have superior outcomes to those who do not. However, assessments of other outcomes may show some benefits to performing concomitant MVPs.

Original languageEnglish (US)
Pages (from-to)91-97
Number of pages7
JournalJournal of Artificial Organs
Volume22
Issue number2
DOIs
StatePublished - Jun 14 2019
Externally publishedYes

Fingerprint

Left ventricular assist devices
Heart-Assist Devices
Mitral Valve Insufficiency
Mitral Valve
Echocardiography
Survival
Heart Transplantation
Heart Failure
Transplantation
Outcome Assessment (Health Care)

Keywords

  • Heart failure
  • Left ventricular assist device
  • Mechanical circulatory support
  • Mitral regurgitation

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering
  • Cardiology and Cardiovascular Medicine

Cite this

Effect of concomitant mitral valve procedures for severe mitral regurgitation during left ventricular assist device implantation. / Kawabori, Masashi; Kurihara, Chitaru; Conyer, Ryan T.; Critsinelis, Andre C.; Sugiura, Tadahisa; Rosengart, Todd; Morgan, Jeffrey A.

In: Journal of Artificial Organs, Vol. 22, No. 2, 14.06.2019, p. 91-97.

Research output: Contribution to journalArticle

Kawabori, Masashi ; Kurihara, Chitaru ; Conyer, Ryan T. ; Critsinelis, Andre C. ; Sugiura, Tadahisa ; Rosengart, Todd ; Morgan, Jeffrey A. / Effect of concomitant mitral valve procedures for severe mitral regurgitation during left ventricular assist device implantation. In: Journal of Artificial Organs. 2019 ; Vol. 22, No. 2. pp. 91-97.
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