Abstract
To determine whether a single seizure permanently affects the brain's susceptibility to further seizures, 27-day-old rats were subjected to a single seizure induced by either an electroshock or the administration of pentylenetetrazol. Three days following the seizure, the rats, along with age- and weight-matched control rats, underwent kindling. The rate of kindling did not differ between the control rats and those rats that had previously experienced a single electroshock or pentylenetetrazol-induced seizure. At the present time, there is no conclusive evidence that a single brief seizure results in permanently increased susceptibility to future convulsions.
Original language | English (US) |
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Pages (from-to) | 853-855 |
Number of pages | 3 |
Journal | Archives of Neurology |
Volume | 41 |
Issue number | 8 |
DOIs | |
State | Published - Aug 1984 |
ASJC Scopus subject areas
- Arts and Humanities (miscellaneous)
- Clinical Neurology