Ecological momentary assessment of the relationship between headache pain intensity and pain interference in women with migraine and obesity

J. Graham Thomas, Jelena Pavlovic, Richard B. Lipton, Julie Roth, Lucille Rathier, Kevin C. O'Leary, Dawn C. Buse, E. Whitney Evans, Dale S. Bond

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Background While pain intensity during migraine headache attacks is known to be a determinant of interference with daily activities, no study has evaluated: (a) the pain intensity-interference association in real-time on a per-headache basis, (b) multiple interference domains, and (c) factors that modify the association. Methods Participants were 116 women with overweight/obesity and migraine seeking behavioral treatment to lose weight and decrease headaches in the Women's Health and Migraine trial. Ecological momentary assessment, via smartphone-based 28-day headache diary, and linear mixed-effects models were used to study associations between pain intensity and total- and domain-specific interference scores using the Brief Pain Inventory. Multiple factors (e.g. pain catastrophizing (PC) and headache management self-efficacy (HMSE)) were evaluated either as independent predictors or moderators of the pain intensity-interference relationship. Results Pain intensity predicted degree of pain interference across all domains either as a main effect (coeff = 0.61-0.78, p < 0.001) or interaction with PC, allodynia, and HMSE (p < 0.05). Older age and greater allodynia consistently predicted higher interference, regardless of pain intensity (coeff = 0.04-0.19, p < 0.05). Conclusions Pain intensity is a consistent predictor of pain interference on migraine headache days. Allodynia, PC, and HMSE moderated the pain intensity-interference relationship, and may be promising targets for interventions to reduce pain interference.

Original languageEnglish (US)
Pages (from-to)1228-1237
Number of pages10
JournalCephalalgia
Volume36
Issue number13
DOIs
StatePublished - Nov 1 2016

Keywords

  • Migraine
  • ecological momentary assessment
  • obesity
  • pain intensity
  • pain interference

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Ecological momentary assessment of the relationship between headache pain intensity and pain interference in women with migraine and obesity'. Together they form a unique fingerprint.

  • Cite this