TY - JOUR
T1 - Early-life course socioeconomic factors and chronic kidney disease
AU - The CKD Life Course Group
AU - Brophy, Patrick D.
AU - Shoham, David A.
AU - Charlton, Jennifer R.
AU - Carmody, J. Bryan
AU - Reidy, Kimberly J.
AU - Harshman, Lyndsay
AU - Segar, Jeffrey
AU - Askenazi, David
AU - Askenazi, David
N1 - Publisher Copyright:
© 2015 National Kidney Foundation, Inc.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Kidney failure or ESRD affects approximately 650,000 Americans, whereas the number with earlier stages of CKD is much higher. Although CKD and ESRD are usually associated with adulthood, it is likely that the initial stages of CKD begin early in life. Many of these pathways are associated with low birth weight and disadvantaged socioeconomic status (SES) in childhood, translating childhood risk into later-life CKD and kidney failure. Social factors are thought to be fundamental causes of disease. Although the relationship between adult SES and CKD has been well established, the role of early childhood SES for CKD risk remains obscure. This review provides a rationale for examining the association between early-life SES and CKD. By collecting data on early-life SES and CKD, the interaction with other periods in the life course could also be studied, allowing for examination of whether SES trajectories (eg, poverty followed by affluence) or cumulative burden (eg, poverty at multiple time points) are more relevant to lifetime CKD risk.
AB - Kidney failure or ESRD affects approximately 650,000 Americans, whereas the number with earlier stages of CKD is much higher. Although CKD and ESRD are usually associated with adulthood, it is likely that the initial stages of CKD begin early in life. Many of these pathways are associated with low birth weight and disadvantaged socioeconomic status (SES) in childhood, translating childhood risk into later-life CKD and kidney failure. Social factors are thought to be fundamental causes of disease. Although the relationship between adult SES and CKD has been well established, the role of early childhood SES for CKD risk remains obscure. This review provides a rationale for examining the association between early-life SES and CKD. By collecting data on early-life SES and CKD, the interaction with other periods in the life course could also be studied, allowing for examination of whether SES trajectories (eg, poverty followed by affluence) or cumulative burden (eg, poverty at multiple time points) are more relevant to lifetime CKD risk.
KW - Chronic kidney disease
KW - Epidemiology
KW - Health disparities
KW - Life course
KW - Socioeconomic status
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U2 - 10.1053/j.ackd.2014.06.006
DO - 10.1053/j.ackd.2014.06.006
M3 - Review article
C2 - 25573508
AN - SCOPUS:84920263374
SN - 1548-5595
VL - 22
SP - 16
EP - 23
JO - Advances in Chronic Kidney Disease
JF - Advances in Chronic Kidney Disease
IS - 1
ER -