E and P selectins are not required for resistance to severe murine lyme arthritis

K. P. Seiler; Y. Ma; J. H. Weis; P. S. Frenette; R. O. Hynes; D. D. Wagner; J. J. Weis

doi:10.1128/.66.9.4557-4559.1998

E and P selectins are not required for resistance to severe murine lyme arthritis

K. P. Seiler, Y. Ma, J. H. Weis, P. S. Frenette, R. O. Hynes, D. D. Wagner, J. J. Weis

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Borrelia burgdorferi-induced arthritis in mice is characterized by tendonitis, synovitis, and inflammatory-cell infiltrate, predominantly of neutrophils. Because genetic deficiency in E and P selectins results in delayed recruitment of nentrophils to sites of inflammation, mice with this deficiency were tested for their response to infection with B. burgdorferi. E and P selectins were not required for the control of B. burgdorferi numbers, nor did deficiency in E and P selectins result in alteration of arthritis severity.

Original language	English (US)
Pages (from-to)	4557-4559
Number of pages	3
Journal	Infection and immunity
Volume	66
Issue number	9
DOIs	https://doi.org/10.1128/.66.9.4557-4559.1998
State	Published - 1998
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/.66.9.4557-4559.1998

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title = "E and P selectins are not required for resistance to severe murine lyme arthritis",

abstract = "Borrelia burgdorferi-induced arthritis in mice is characterized by tendonitis, synovitis, and inflammatory-cell infiltrate, predominantly of neutrophils. Because genetic deficiency in E and P selectins results in delayed recruitment of nentrophils to sites of inflammation, mice with this deficiency were tested for their response to infection with B. burgdorferi. E and P selectins were not required for the control of B. burgdorferi numbers, nor did deficiency in E and P selectins result in alteration of arthritis severity.",

author = "Seiler, {K. P.} and Y. Ma and Weis, {J. H.} and Frenette, {P. S.} and Hynes, {R. O.} and Wagner, {D. D.} and Weis, {J. J.}",

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T1 - E and P selectins are not required for resistance to severe murine lyme arthritis

AU - Seiler, K. P.

AU - Ma, Y.

AU - Weis, J. H.

AU - Frenette, P. S.

AU - Hynes, R. O.

AU - Wagner, D. D.

AU - Weis, J. J.

PY - 1998

Y1 - 1998

N2 - Borrelia burgdorferi-induced arthritis in mice is characterized by tendonitis, synovitis, and inflammatory-cell infiltrate, predominantly of neutrophils. Because genetic deficiency in E and P selectins results in delayed recruitment of nentrophils to sites of inflammation, mice with this deficiency were tested for their response to infection with B. burgdorferi. E and P selectins were not required for the control of B. burgdorferi numbers, nor did deficiency in E and P selectins result in alteration of arthritis severity.

AB - Borrelia burgdorferi-induced arthritis in mice is characterized by tendonitis, synovitis, and inflammatory-cell infiltrate, predominantly of neutrophils. Because genetic deficiency in E and P selectins results in delayed recruitment of nentrophils to sites of inflammation, mice with this deficiency were tested for their response to infection with B. burgdorferi. E and P selectins were not required for the control of B. burgdorferi numbers, nor did deficiency in E and P selectins result in alteration of arthritis severity.

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AN - SCOPUS:0031719491

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EP - 4559

JO - Infection and immunity

JF - Infection and immunity

IS - 9

ER -

E and P selectins are not required for resistance to severe murine lyme arthritis

Abstract

ASJC Scopus subject areas

UN SDGs

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