Dysregulation of TFEB contributes to manganese-induced autophagic failure and mitochondrial dysfunction in astrocytes

Medicine & Life Sciences

• Manganese 100%
• Astrocytes 76%
• Transcription Factors 62%
• Autophagy 44%
• Reactive Oxygen Species 22%
• Heavy Metals 22%
• Sirolimus 19%
• Neurodegenerative Diseases 16%
• Hanks Balanced Salt Solution 15%
• Mitochondria 15%
• Lysosome-Associated Membrane Glycoproteins 13%
• Macroautophagy 12%
• paraform 12%
• Cathepsin D 12%
• Eagles 12%
• Beclin-1 11%
• Microtubule-Associated Proteins 11%
• Mitogen-Activated Protein Kinase 3 10%
• Propidium 10%
• Glial Fibrillary Acidic Protein 10%
• Green Fluorescent Proteins 9%
• Lysosomes 9%
• Transmission Electron Microscopy 9%
• L-Lactate Dehydrogenase 9%
• Oxygen Consumption 9%
• Phosphates 8%
• Epidemiologic Studies 7%
• Phosphotransferases 7%
• Light 6%
• Clinical Studies 6%
• Therapeutics 1%