Dynamics of transcription and mRNA export

Xavier Darzacq, Robert H. Singer, Yaron Shav-Tal

Research output: Contribution to journalReview article

46 Scopus citations

Abstract

Understanding the different molecular mechanisms responsible for gene expression has been a central interest of molecular biologists for several decades. Transcription, the initial step of gene expression, consists of converting the genetic code into a dynamic messenger RNA that will specify a required cellular function following translocation to the cytoplasm and translation. We now possess an in-depth understanding of the mechanism and regulations of transcription. By contrast, an understanding of the dynamics of an individual gene's expression in real time is just beginning to emerge following recent technological developments.

Original languageEnglish (US)
Pages (from-to)332-339
Number of pages8
JournalCurrent Opinion in Cell Biology
Volume17
Issue number3
DOIs
StatePublished - Jun 1 2005

ASJC Scopus subject areas

  • Cell Biology

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