Drug Metabolism as a Community Effort

R. Hitchings, Libusha Kelly

Research output: Contribution to journalShort survey


Levodopa (L-dopa) is the primary treatment for Parkinson's disease. The gut microbiome can metabolize levodopa, potentially leading to decreased efficacy and side effects, but responsible bacteria were unknown. Maini Rekdal et al. (2019) characterize enzymes in two gut bacteria that sequentially metabolize L-dopa and identify a novel inhibitor that may improve outcomes.

Original languageEnglish (US)
Pages (from-to)235-237
Number of pages3
JournalCell metabolism
Issue number2
Publication statusPublished - Aug 6 2019


ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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