Drug-induced liver disease in older adults

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The elderly population consumes more prescription and over-the-counter medications than any other segment of the population. As a result, they are more prone to adverse drug events and susceptible to drug induced liver injury. Further, age related changes in the liver also influence drug metabolism, contributing to an increased risk of adverse effects. The spectrum of drug induced liver disease can vary from frequently noted mild abnormality of liver function tests to occasional severe injury, resulting in death. In the elderly, drugs must be considered as the most likely basis for abnormal liver function. Awareness of this fact, coupled with appropriate use of medications and close monitoring of liver function tests will minimize the magnitude of this problem.

Original languageEnglish (US)
JournalPractical Gastroenterology
Volume25
Issue number3
StatePublished - 2001
Externally publishedYes

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Chemical and Drug Induced Liver Injury
Liver Function Tests
Liver
Drug-Related Side Effects and Adverse Reactions
Pharmaceutical Preparations
Population
Prescriptions
Wounds and Injuries

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Drug-induced liver disease in older adults. / Dharmarajan, Thiruvinvamalai S.; Pitchumoni, C. S.

In: Practical Gastroenterology, Vol. 25, No. 3, 2001.

Research output: Contribution to journalArticle

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