Does umbilical vein catheterization lead to portal venous thrombosis? Prospective US evaluation in 100 neonates

Ji Hye Kim, Young Seok Lee, Sang Hee Kim, Seon Kyu Lee, Myung Kwan Lim, Hyung Sik Kim

Research output: Contribution to journalArticle

115 Citations (Scopus)

Abstract

PURPOSE: To establish, by means of serial ultrasonography (US), the incidence and natural history of neonatal portal venous thrombosis associated with catheterization of the umbilical vein and to evaluate the potential risk factors predisposing patients to thrombus formation. MATERIALS AND METHODS: Neonates who had undergone umbilical vein catheterization were studied. US was performed at 2-7-day intervals, before and after the removal of the catheter, until clot resolution or hospital discharge. The presence of portal venous thrombosis and temporal evolution were noted, and various risk factors were analyzed. RESULTS: US demonstrated clinically silent portal venous thrombosis in 43 (43%) of 100 neonates. Follow-up US revealed complete or partial resolution in 20 (56%) of 36 babies. A significant (P = .024) correlation was found between the initial size of the thrombi and spontaneous clot resolution. Statistically significant risk factors were catheterization for more than 6 days (P = .001) and transfusion (P = .019). CONCLUSION: Portal venous thrombosis is frequently associated with the placement of an umbilical venous catheter, and spontaneous resolution is expected in many cases. The duration of catheter placement should be minimized, and US monitoring is recommended as a guide to catheter removal.

Original languageEnglish (US)
Pages (from-to)645-650
Number of pages6
JournalRADIOLOGY
Volume219
Issue number3
DOIs
StatePublished - Jun 2001
Externally publishedYes

Fingerprint

Umbilical Veins
Catheterization
Venous Thrombosis
Ultrasonography
Newborn Infant
Catheters
Thrombosis
Umbilicus
Natural History
Incidence

Keywords

  • Catheters and catheterization, complications, 957.442
  • Catheters and catheterization, in infants and children, 957.126
  • Portal vein, thrombosis, 957.442
  • Portal vein, US, 957.1298, 957.12983
  • Ultrasound (US), in infants and children, 957.1298, 957.12983

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Does umbilical vein catheterization lead to portal venous thrombosis? Prospective US evaluation in 100 neonates. / Kim, Ji Hye; Lee, Young Seok; Kim, Sang Hee; Lee, Seon Kyu; Lim, Myung Kwan; Kim, Hyung Sik.

In: RADIOLOGY, Vol. 219, No. 3, 06.2001, p. 645-650.

Research output: Contribution to journalArticle

Kim, Ji Hye ; Lee, Young Seok ; Kim, Sang Hee ; Lee, Seon Kyu ; Lim, Myung Kwan ; Kim, Hyung Sik. / Does umbilical vein catheterization lead to portal venous thrombosis? Prospective US evaluation in 100 neonates. In: RADIOLOGY. 2001 ; Vol. 219, No. 3. pp. 645-650.
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