Does scopolamine directly impair memory?

E. Grober, R. M. Leipzig, Richard B. Lipton, W. Wisniewski, M. Schroeder, P. Davies, W. Ritter, Herman Buschke

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Enhanced cued recall, a procedure which circumvents inattention and induces semantic processing, was used to determine if scopolamine produces direct impairment of specific memory mechanisms or indirect impairment of memory secondary to impairment of other cognitive processes. In two studies, cognitively normal young adults given moderate or high doses of scopolamine maintained maximum cued recall in spite of a dose-dependent decrement in free recall. This finding suggests that cholinergic blockade may impair memory indirectly through effects on other cognitive processes.

Original languageEnglish (US)
Pages (from-to)327-335
Number of pages9
JournalJournal of Cognitive Neuroscience
Volume1
Issue number4
StatePublished - 1989

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Scopolamine Hydrobromide
Semantics
Cholinergic Agents
Young Adult

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology

Cite this

Grober, E., Leipzig, R. M., Lipton, R. B., Wisniewski, W., Schroeder, M., Davies, P., ... Buschke, H. (1989). Does scopolamine directly impair memory? Journal of Cognitive Neuroscience, 1(4), 327-335.

Does scopolamine directly impair memory? / Grober, E.; Leipzig, R. M.; Lipton, Richard B.; Wisniewski, W.; Schroeder, M.; Davies, P.; Ritter, W.; Buschke, Herman.

In: Journal of Cognitive Neuroscience, Vol. 1, No. 4, 1989, p. 327-335.

Research output: Contribution to journalArticle

Grober, E, Leipzig, RM, Lipton, RB, Wisniewski, W, Schroeder, M, Davies, P, Ritter, W & Buschke, H 1989, 'Does scopolamine directly impair memory?', Journal of Cognitive Neuroscience, vol. 1, no. 4, pp. 327-335.
Grober E, Leipzig RM, Lipton RB, Wisniewski W, Schroeder M, Davies P et al. Does scopolamine directly impair memory? Journal of Cognitive Neuroscience. 1989;1(4):327-335.
Grober, E. ; Leipzig, R. M. ; Lipton, Richard B. ; Wisniewski, W. ; Schroeder, M. ; Davies, P. ; Ritter, W. ; Buschke, Herman. / Does scopolamine directly impair memory?. In: Journal of Cognitive Neuroscience. 1989 ; Vol. 1, No. 4. pp. 327-335.
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