Does regular multivitamin (MVT) use increase serum levels of vitamins in community healthy elderly?

Research output: Contribution to journalArticle

Abstract

Macronutrient and micronutrient deficiencies are common in the elderly living in North America. The present study examined the relationship between daily MVT use and serum levels of selected vitamins in cognitively normal, healthy elderly. Fasting blood samples were collected from 19 volunteers (63-88 yr). Group 1 elderly (6 males & 6 females, 75.4 ± 1.0 yr) did not consume MVT while group 2 elderly (5 males and 2 females, 77.3 ± 3.3 yr) consumed a standard MVT daily. Subjects in Group 1 and 2 did not differ significantly by age, race, marital status, or education level. Serum vitamin C and E values were significantly increased by daily MVT (P<0.0200 & P<0.0028, respectively) while serum vitamin B12, folate and β-carotene levels were unchanged by daily MVT. Regression analyses determined a significant positive relationship between daily MVT use and the increase in serum vitamin C (p<0.0401) and (P<0.0055), no relationship between daily MVT use and serum B12 and folate, and a significant negative relationship between daily MVT use and serum β-carotene (P<0.0007). Our study suggests that regular MVT use does not improve serum levels of all vitamins in healthy, cognitively normal elderly. Periodic assessment of vitamin status may be justified in this age group.

Original languageEnglish (US)
JournalFASEB Journal
Volume12
Issue number5
StatePublished - Mar 20 1998
Externally publishedYes

Fingerprint

blood serum
Vitamins
vitamins
Carotenoids
Folic Acid
Ascorbic Acid
Serum
Micronutrients
Vitamin B 12
Vitamin E
carotenes
folic acid
Blood
Education
ascorbic acid
marital status
Marital Status
educational status
vitamin B12
North America

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology

Cite this

Does regular multivitamin (MVT) use increase serum levels of vitamins in community healthy elderly? / Dharmarajan, Thiruvinvamalai S.; Kanagala, Madhusudhana R.; Rajendran, R.; Norkus, E. P.

In: FASEB Journal, Vol. 12, No. 5, 20.03.1998.

Research output: Contribution to journalArticle

@article{f9079742a50e4f66a17567de032b8d7c,
title = "Does regular multivitamin (MVT) use increase serum levels of vitamins in community healthy elderly?",
abstract = "Macronutrient and micronutrient deficiencies are common in the elderly living in North America. The present study examined the relationship between daily MVT use and serum levels of selected vitamins in cognitively normal, healthy elderly. Fasting blood samples were collected from 19 volunteers (63-88 yr). Group 1 elderly (6 males & 6 females, 75.4 ± 1.0 yr) did not consume MVT while group 2 elderly (5 males and 2 females, 77.3 ± 3.3 yr) consumed a standard MVT daily. Subjects in Group 1 and 2 did not differ significantly by age, race, marital status, or education level. Serum vitamin C and E values were significantly increased by daily MVT (P<0.0200 & P<0.0028, respectively) while serum vitamin B12, folate and β-carotene levels were unchanged by daily MVT. Regression analyses determined a significant positive relationship between daily MVT use and the increase in serum vitamin C (p<0.0401) and (P<0.0055), no relationship between daily MVT use and serum B12 and folate, and a significant negative relationship between daily MVT use and serum β-carotene (P<0.0007). Our study suggests that regular MVT use does not improve serum levels of all vitamins in healthy, cognitively normal elderly. Periodic assessment of vitamin status may be justified in this age group.",
author = "Dharmarajan, {Thiruvinvamalai S.} and Kanagala, {Madhusudhana R.} and R. Rajendran and Norkus, {E. P.}",
year = "1998",
month = "3",
day = "20",
language = "English (US)",
volume = "12",
journal = "FASEB Journal",
issn = "0892-6638",
publisher = "FASEB",
number = "5",

}

TY - JOUR

T1 - Does regular multivitamin (MVT) use increase serum levels of vitamins in community healthy elderly?

AU - Dharmarajan, Thiruvinvamalai S.

AU - Kanagala, Madhusudhana R.

AU - Rajendran, R.

AU - Norkus, E. P.

PY - 1998/3/20

Y1 - 1998/3/20

N2 - Macronutrient and micronutrient deficiencies are common in the elderly living in North America. The present study examined the relationship between daily MVT use and serum levels of selected vitamins in cognitively normal, healthy elderly. Fasting blood samples were collected from 19 volunteers (63-88 yr). Group 1 elderly (6 males & 6 females, 75.4 ± 1.0 yr) did not consume MVT while group 2 elderly (5 males and 2 females, 77.3 ± 3.3 yr) consumed a standard MVT daily. Subjects in Group 1 and 2 did not differ significantly by age, race, marital status, or education level. Serum vitamin C and E values were significantly increased by daily MVT (P<0.0200 & P<0.0028, respectively) while serum vitamin B12, folate and β-carotene levels were unchanged by daily MVT. Regression analyses determined a significant positive relationship between daily MVT use and the increase in serum vitamin C (p<0.0401) and (P<0.0055), no relationship between daily MVT use and serum B12 and folate, and a significant negative relationship between daily MVT use and serum β-carotene (P<0.0007). Our study suggests that regular MVT use does not improve serum levels of all vitamins in healthy, cognitively normal elderly. Periodic assessment of vitamin status may be justified in this age group.

AB - Macronutrient and micronutrient deficiencies are common in the elderly living in North America. The present study examined the relationship between daily MVT use and serum levels of selected vitamins in cognitively normal, healthy elderly. Fasting blood samples were collected from 19 volunteers (63-88 yr). Group 1 elderly (6 males & 6 females, 75.4 ± 1.0 yr) did not consume MVT while group 2 elderly (5 males and 2 females, 77.3 ± 3.3 yr) consumed a standard MVT daily. Subjects in Group 1 and 2 did not differ significantly by age, race, marital status, or education level. Serum vitamin C and E values were significantly increased by daily MVT (P<0.0200 & P<0.0028, respectively) while serum vitamin B12, folate and β-carotene levels were unchanged by daily MVT. Regression analyses determined a significant positive relationship between daily MVT use and the increase in serum vitamin C (p<0.0401) and (P<0.0055), no relationship between daily MVT use and serum B12 and folate, and a significant negative relationship between daily MVT use and serum β-carotene (P<0.0007). Our study suggests that regular MVT use does not improve serum levels of all vitamins in healthy, cognitively normal elderly. Periodic assessment of vitamin status may be justified in this age group.

UR - http://www.scopus.com/inward/record.url?scp=33749295467&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33749295467&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33749295467

VL - 12

JO - FASEB Journal

JF - FASEB Journal

SN - 0892-6638

IS - 5

ER -