TY - JOUR
T1 - Do patients with obstructive sleep apnea have an increased risk of desaturation during induction of anesthesia for weight loss surgery?
AU - Eikermann, Matthias
AU - Garzon-Serrano, Jaime
AU - Kwo, Jean
AU - Grosse-Sundrup, Martina
AU - Schmidt, Ulrich
AU - Bigatello, Luca
N1 - Publisher Copyright:
© Eikermann et al.
PY - 2010/3/1
Y1 - 2010/3/1
N2 - Background: Obstructive sleep apnea (OSA) is an independent risk factor to develop perioperative complications during weight loss surgery, but the mechanisms are unclear. It is possible, that patients with OSA have a higher incidence of desaturation during induction of anesthesia. Methods: We enrolled 100 morbidly obese (body mass index: 53±10) adult patients undergoing open bariatric surgery in a prospective study. At least 1 h before induction of anesthesia, peripheral oxygen saturation (SpO2) was measured by an oximetry finger probe in the sitting and supine positions, and Mallampati score was taken. Oxygen saturation was recorded also during induction of anesthesia, and nadir values were analyzed, and the STOP-BANG questionnaire was applied. Results: Thirty-six patients presented with clinical suspicion of OSA. Body weight predicted oxygen saturation in the supine and sitting position, prior to induction of anesthesia. Nadir oxygen saturation during induction of anesthesia was considerably higher in patients with clinical suspicion of OSA, a significant finding that persisted as a trend after correction for age, gender and BMI. The Mallampati score was an independent predictor of OSA, even in morbidly obese patients scheduled for weight loss surgery. Conclusions: Morbidly obese patients presenting for weight loss surgery have a significant risk to desaturate during induction of anesthesia. A history of OSA does not independently increase the risk of desaturation during induction of anesthesia, if the appropriate precautions are being taken.
AB - Background: Obstructive sleep apnea (OSA) is an independent risk factor to develop perioperative complications during weight loss surgery, but the mechanisms are unclear. It is possible, that patients with OSA have a higher incidence of desaturation during induction of anesthesia. Methods: We enrolled 100 morbidly obese (body mass index: 53±10) adult patients undergoing open bariatric surgery in a prospective study. At least 1 h before induction of anesthesia, peripheral oxygen saturation (SpO2) was measured by an oximetry finger probe in the sitting and supine positions, and Mallampati score was taken. Oxygen saturation was recorded also during induction of anesthesia, and nadir values were analyzed, and the STOP-BANG questionnaire was applied. Results: Thirty-six patients presented with clinical suspicion of OSA. Body weight predicted oxygen saturation in the supine and sitting position, prior to induction of anesthesia. Nadir oxygen saturation during induction of anesthesia was considerably higher in patients with clinical suspicion of OSA, a significant finding that persisted as a trend after correction for age, gender and BMI. The Mallampati score was an independent predictor of OSA, even in morbidly obese patients scheduled for weight loss surgery. Conclusions: Morbidly obese patients presenting for weight loss surgery have a significant risk to desaturate during induction of anesthesia. A history of OSA does not independently increase the risk of desaturation during induction of anesthesia, if the appropriate precautions are being taken.
KW - Anesthesia
KW - Bariatric surgery
KW - Obesity
KW - Obstructive sleep apnea
KW - Oximetry
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U2 - 10.2174/1874306401004010058
DO - 10.2174/1874306401004010058
M3 - Article
AN - SCOPUS:84987771108
SN - 1874-3064
VL - 4
SP - 58
EP - 62
JO - Open Respiratory Medicine Journal
JF - Open Respiratory Medicine Journal
ER -