Do all components of the metabolic syndrome cluster together in U.S. Hispanics/Latinos? Results from the Hispanic Community Health study/Study of Latinos

Maria M. Llabre, William Arguelles, Neil Schneiderman, Linda C. Gallo, Martha L. Daviglus, Earle C. Chambers, Daniela Sotres-Alvarez, Diana A. Chirinos, Gregory A. Talavera, Sheila F. Castaneda, Scott C. Roesch, Gerardo Heiss

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Purpose: Metabolic syndrome (MetS), the clustering of several risk factors for cardiovascular disease, is highly prevalent in Hispanics/Latinos. We tested whether all components significantly loaded on the syndrome in Hispanics/Latinos and whether their contribution differed by sex and Hispanic ancestry. We also examined associations of MetS with prevalent diabetes and coronary heart disease in Hispanics/Latinos. Methods: Data were obtained from a population-based cohort of n=15,823 participants in the HCHS/SOL study who self-identified as being of Central American, Cuban, Dominican, Mexican American, Puerto Rican, or South American ancestry and were aged 18 to 74years at screening. Results: A latent variable model of waist circumference, systolic and diastolic blood pressure, triglycerides, high-density lipoprotein cholesterol (HDL-C), and fasting glucose fit the data in men and women, but the contribution of HDL-C was weak. No difference in the latent model of MetS was detected across Hispanic/Latino ancestry groups. MetS was significantly associated with diabetes and coronary heart disease. Conclusions: Our results indicate that similar criteria for MetS may be applied across Hispanic/Latino ancestry groups but call into question the role of HDL-C in classifying the MetS in Hispanics/Latinos.

Original languageEnglish (US)
Pages (from-to)480-485
Number of pages6
JournalAnnals of Epidemiology
Volume25
Issue number7
DOIs
StatePublished - Jul 1 2015

Keywords

  • Hispanics
  • Lipids
  • Metabolic syndrome

ASJC Scopus subject areas

  • Epidemiology

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