Do all components of the metabolic syndrome cluster together in U.S. Hispanics/Latinos? Results from the Hispanic Community Health study/Study of Latinos

Maria M. Llabre, William Arguelles, Neil Schneiderman, Linda C. Gallo, Martha L. Daviglus, Earle C. Chambers, Daniela Sotres-Alvarez, Diana A. Chirinos, Gregory A. Talavera, Sheila F. Castaneda, Scott C. Roesch, Gerardo Heiss

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Purpose: Metabolic syndrome (MetS), the clustering of several risk factors for cardiovascular disease, is highly prevalent in Hispanics/Latinos. We tested whether all components significantly loaded on the syndrome in Hispanics/Latinos and whether their contribution differed by sex and Hispanic ancestry. We also examined associations of MetS with prevalent diabetes and coronary heart disease in Hispanics/Latinos. Methods: Data were obtained from a population-based cohort of n=15,823 participants in the HCHS/SOL study who self-identified as being of Central American, Cuban, Dominican, Mexican American, Puerto Rican, or South American ancestry and were aged 18 to 74years at screening. Results: A latent variable model of waist circumference, systolic and diastolic blood pressure, triglycerides, high-density lipoprotein cholesterol (HDL-C), and fasting glucose fit the data in men and women, but the contribution of HDL-C was weak. No difference in the latent model of MetS was detected across Hispanic/Latino ancestry groups. MetS was significantly associated with diabetes and coronary heart disease. Conclusions: Our results indicate that similar criteria for MetS may be applied across Hispanic/Latino ancestry groups but call into question the role of HDL-C in classifying the MetS in Hispanics/Latinos.

Original languageEnglish (US)
Pages (from-to)480-485
Number of pages6
JournalAnnals of Epidemiology
Volume25
Issue number7
DOIs
StatePublished - Jul 1 2015

Fingerprint

Hispanic Americans
Health
HDL Cholesterol
Coronary Disease
Blood Pressure
Waist Circumference
Cluster Analysis
Fasting
Triglycerides
Cardiovascular Diseases

Keywords

  • Hispanics
  • Lipids
  • Metabolic syndrome

ASJC Scopus subject areas

  • Epidemiology

Cite this

Do all components of the metabolic syndrome cluster together in U.S. Hispanics/Latinos? Results from the Hispanic Community Health study/Study of Latinos. / Llabre, Maria M.; Arguelles, William; Schneiderman, Neil; Gallo, Linda C.; Daviglus, Martha L.; Chambers, Earle C.; Sotres-Alvarez, Daniela; Chirinos, Diana A.; Talavera, Gregory A.; Castaneda, Sheila F.; Roesch, Scott C.; Heiss, Gerardo.

In: Annals of Epidemiology, Vol. 25, No. 7, 01.07.2015, p. 480-485.

Research output: Contribution to journalArticle

Llabre, MM, Arguelles, W, Schneiderman, N, Gallo, LC, Daviglus, ML, Chambers, EC, Sotres-Alvarez, D, Chirinos, DA, Talavera, GA, Castaneda, SF, Roesch, SC & Heiss, G 2015, 'Do all components of the metabolic syndrome cluster together in U.S. Hispanics/Latinos? Results from the Hispanic Community Health study/Study of Latinos', Annals of Epidemiology, vol. 25, no. 7, pp. 480-485. https://doi.org/10.1016/j.annepidem.2015.02.010
Llabre, Maria M. ; Arguelles, William ; Schneiderman, Neil ; Gallo, Linda C. ; Daviglus, Martha L. ; Chambers, Earle C. ; Sotres-Alvarez, Daniela ; Chirinos, Diana A. ; Talavera, Gregory A. ; Castaneda, Sheila F. ; Roesch, Scott C. ; Heiss, Gerardo. / Do all components of the metabolic syndrome cluster together in U.S. Hispanics/Latinos? Results from the Hispanic Community Health study/Study of Latinos. In: Annals of Epidemiology. 2015 ; Vol. 25, No. 7. pp. 480-485.
@article{d44be48f56024de2aaef605199a84b5a,
title = "Do all components of the metabolic syndrome cluster together in U.S. Hispanics/Latinos? Results from the Hispanic Community Health study/Study of Latinos",
abstract = "Purpose: Metabolic syndrome (MetS), the clustering of several risk factors for cardiovascular disease, is highly prevalent in Hispanics/Latinos. We tested whether all components significantly loaded on the syndrome in Hispanics/Latinos and whether their contribution differed by sex and Hispanic ancestry. We also examined associations of MetS with prevalent diabetes and coronary heart disease in Hispanics/Latinos. Methods: Data were obtained from a population-based cohort of n=15,823 participants in the HCHS/SOL study who self-identified as being of Central American, Cuban, Dominican, Mexican American, Puerto Rican, or South American ancestry and were aged 18 to 74years at screening. Results: A latent variable model of waist circumference, systolic and diastolic blood pressure, triglycerides, high-density lipoprotein cholesterol (HDL-C), and fasting glucose fit the data in men and women, but the contribution of HDL-C was weak. No difference in the latent model of MetS was detected across Hispanic/Latino ancestry groups. MetS was significantly associated with diabetes and coronary heart disease. Conclusions: Our results indicate that similar criteria for MetS may be applied across Hispanic/Latino ancestry groups but call into question the role of HDL-C in classifying the MetS in Hispanics/Latinos.",
keywords = "Hispanics, Lipids, Metabolic syndrome",
author = "Llabre, {Maria M.} and William Arguelles and Neil Schneiderman and Gallo, {Linda C.} and Daviglus, {Martha L.} and Chambers, {Earle C.} and Daniela Sotres-Alvarez and Chirinos, {Diana A.} and Talavera, {Gregory A.} and Castaneda, {Sheila F.} and Roesch, {Scott C.} and Gerardo Heiss",
year = "2015",
month = "7",
day = "1",
doi = "10.1016/j.annepidem.2015.02.010",
language = "English (US)",
volume = "25",
pages = "480--485",
journal = "Annals of Epidemiology",
issn = "1047-2797",
publisher = "Elsevier Inc.",
number = "7",

}

TY - JOUR

T1 - Do all components of the metabolic syndrome cluster together in U.S. Hispanics/Latinos? Results from the Hispanic Community Health study/Study of Latinos

AU - Llabre, Maria M.

AU - Arguelles, William

AU - Schneiderman, Neil

AU - Gallo, Linda C.

AU - Daviglus, Martha L.

AU - Chambers, Earle C.

AU - Sotres-Alvarez, Daniela

AU - Chirinos, Diana A.

AU - Talavera, Gregory A.

AU - Castaneda, Sheila F.

AU - Roesch, Scott C.

AU - Heiss, Gerardo

PY - 2015/7/1

Y1 - 2015/7/1

N2 - Purpose: Metabolic syndrome (MetS), the clustering of several risk factors for cardiovascular disease, is highly prevalent in Hispanics/Latinos. We tested whether all components significantly loaded on the syndrome in Hispanics/Latinos and whether their contribution differed by sex and Hispanic ancestry. We also examined associations of MetS with prevalent diabetes and coronary heart disease in Hispanics/Latinos. Methods: Data were obtained from a population-based cohort of n=15,823 participants in the HCHS/SOL study who self-identified as being of Central American, Cuban, Dominican, Mexican American, Puerto Rican, or South American ancestry and were aged 18 to 74years at screening. Results: A latent variable model of waist circumference, systolic and diastolic blood pressure, triglycerides, high-density lipoprotein cholesterol (HDL-C), and fasting glucose fit the data in men and women, but the contribution of HDL-C was weak. No difference in the latent model of MetS was detected across Hispanic/Latino ancestry groups. MetS was significantly associated with diabetes and coronary heart disease. Conclusions: Our results indicate that similar criteria for MetS may be applied across Hispanic/Latino ancestry groups but call into question the role of HDL-C in classifying the MetS in Hispanics/Latinos.

AB - Purpose: Metabolic syndrome (MetS), the clustering of several risk factors for cardiovascular disease, is highly prevalent in Hispanics/Latinos. We tested whether all components significantly loaded on the syndrome in Hispanics/Latinos and whether their contribution differed by sex and Hispanic ancestry. We also examined associations of MetS with prevalent diabetes and coronary heart disease in Hispanics/Latinos. Methods: Data were obtained from a population-based cohort of n=15,823 participants in the HCHS/SOL study who self-identified as being of Central American, Cuban, Dominican, Mexican American, Puerto Rican, or South American ancestry and were aged 18 to 74years at screening. Results: A latent variable model of waist circumference, systolic and diastolic blood pressure, triglycerides, high-density lipoprotein cholesterol (HDL-C), and fasting glucose fit the data in men and women, but the contribution of HDL-C was weak. No difference in the latent model of MetS was detected across Hispanic/Latino ancestry groups. MetS was significantly associated with diabetes and coronary heart disease. Conclusions: Our results indicate that similar criteria for MetS may be applied across Hispanic/Latino ancestry groups but call into question the role of HDL-C in classifying the MetS in Hispanics/Latinos.

KW - Hispanics

KW - Lipids

KW - Metabolic syndrome

UR - http://www.scopus.com/inward/record.url?scp=84930047743&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84930047743&partnerID=8YFLogxK

U2 - 10.1016/j.annepidem.2015.02.010

DO - 10.1016/j.annepidem.2015.02.010

M3 - Article

C2 - 25818844

AN - SCOPUS:84930047743

VL - 25

SP - 480

EP - 485

JO - Annals of Epidemiology

JF - Annals of Epidemiology

SN - 1047-2797

IS - 7

ER -