Abstract
The auditory mismatch negativity (MMN) component of event-related potentials (ERPs) has served as a neural index of auditory change detection. MMN is elicited by presentation of infrequent (deviant) sounds randomly interspersed among frequent (standard) sounds. Deviants elicit a larger negative deflection in the ERP waveform compared to the standard. There is considerable debate as to whether the neural mechanism of this change detection response is due to release from neural adaptation (neural adaptation hypothesis) or from a prediction error signal (predictive coding hypothesis). Previous studies have not been able to distinguish between these explanations because paradigms typically confound the two. The current study disambiguated effects of stimulus-specific adaptation from expectation violation using a unique stimulus design that compared expectation violation responses that did and did not involve stimulus change. The expectation violation response without the stimulus change differed in timing, scalp distribution, and attentional modulation from the more typical MMN response. There is insufficient evidence from the current study to suggest that the negative deflection elicited by the expectation violation alone includes the MMN. Thus, we offer a novel hypothesis that the expectation violation response reflects a fundamentally different neural substrate than that attributed to the canonical MMN.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-13 |
| Number of pages | 13 |
| Journal | Brain Topography |
| DOIs | |
| State | Accepted/In press - Oct 17 2016 |
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Keywords
- Attention
- Event-related brain potentials (ERPs)
- Expectation
- Mismatch negativity (MMN)
- Novelty detection
- Predictive coding
ASJC Scopus subject areas
- Anatomy
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging
- Neurology
- Clinical Neurology
Cite this
Distinguishing Neural Adaptation and Predictive Coding Hypotheses in Auditory Change Detection. / Symonds, Renée M.; Lee, Wei Wei; Kohn, Adam; Schwartz, Odelia; Witkowski, Sarah; Sussman, Elyse S.
In: Brain Topography, 17.10.2016, p. 1-13.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Distinguishing Neural Adaptation and Predictive Coding Hypotheses in Auditory Change Detection
AU - Symonds, Renée M.
AU - Lee, Wei Wei
AU - Kohn, Adam
AU - Schwartz, Odelia
AU - Witkowski, Sarah
AU - Sussman, Elyse S.
PY - 2016/10/17
Y1 - 2016/10/17
N2 - The auditory mismatch negativity (MMN) component of event-related potentials (ERPs) has served as a neural index of auditory change detection. MMN is elicited by presentation of infrequent (deviant) sounds randomly interspersed among frequent (standard) sounds. Deviants elicit a larger negative deflection in the ERP waveform compared to the standard. There is considerable debate as to whether the neural mechanism of this change detection response is due to release from neural adaptation (neural adaptation hypothesis) or from a prediction error signal (predictive coding hypothesis). Previous studies have not been able to distinguish between these explanations because paradigms typically confound the two. The current study disambiguated effects of stimulus-specific adaptation from expectation violation using a unique stimulus design that compared expectation violation responses that did and did not involve stimulus change. The expectation violation response without the stimulus change differed in timing, scalp distribution, and attentional modulation from the more typical MMN response. There is insufficient evidence from the current study to suggest that the negative deflection elicited by the expectation violation alone includes the MMN. Thus, we offer a novel hypothesis that the expectation violation response reflects a fundamentally different neural substrate than that attributed to the canonical MMN.
AB - The auditory mismatch negativity (MMN) component of event-related potentials (ERPs) has served as a neural index of auditory change detection. MMN is elicited by presentation of infrequent (deviant) sounds randomly interspersed among frequent (standard) sounds. Deviants elicit a larger negative deflection in the ERP waveform compared to the standard. There is considerable debate as to whether the neural mechanism of this change detection response is due to release from neural adaptation (neural adaptation hypothesis) or from a prediction error signal (predictive coding hypothesis). Previous studies have not been able to distinguish between these explanations because paradigms typically confound the two. The current study disambiguated effects of stimulus-specific adaptation from expectation violation using a unique stimulus design that compared expectation violation responses that did and did not involve stimulus change. The expectation violation response without the stimulus change differed in timing, scalp distribution, and attentional modulation from the more typical MMN response. There is insufficient evidence from the current study to suggest that the negative deflection elicited by the expectation violation alone includes the MMN. Thus, we offer a novel hypothesis that the expectation violation response reflects a fundamentally different neural substrate than that attributed to the canonical MMN.
KW - Attention
KW - Event-related brain potentials (ERPs)
KW - Expectation
KW - Mismatch negativity (MMN)
KW - Novelty detection
KW - Predictive coding
UR - http://www.scopus.com/inward/record.url?scp=84991619005&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84991619005&partnerID=8YFLogxK
U2 - 10.1007/s10548-016-0529-8
DO - 10.1007/s10548-016-0529-8
M3 - Article
AN - SCOPUS:84991619005
SP - 1
EP - 13
JO - Brain Topography
JF - Brain Topography
SN - 0896-0267
ER -