Dissemination and implementation of comparative effectiveness evidence: Key informant interviews with Clinical and Translational Science Award institutions

Elaine H. Morrato, Thomas W. Concannon, Paul Meissner, Nilay D. Shah, Barbara J. Turner

Research output: Contribution to journalArticle

11 Scopus citations


Aim: To identify ongoing practices and opportunities for improving national comparative effectiveness research (CER) translation through dissemination and implementation (D&I) via NIH-funded Clinical and Translational Science Award (CTSA) institutions. Materials & methods: Key informant interviews were conducted with 18 CTSA grantees sampled to represent a range of D&I efforts. Results & conclusions: The institutional representatives endorsed fostering CER translation nationally via the CTSA Consortium. However, five themes emerged from the interviews as barriers to CER D&I: lack of institutional awareness, insufficient capacity, lack of established D&I methods, confusion among stakeholders about what CER actually is and limited funding opportunities. Interviewees offered two key recommendations to improve CER translation: development of a centralized clearing house to facilitate the diffusion of CER D&I resources and methods across CTSA institutions; and formalization of the national CTSA network to leverage existing community engagement relationships and resources for the purpose of adapting and disseminating robust CER evidence locally with providers, patients and healthcare systems.

Original languageEnglish (US)
Pages (from-to)185-194
Number of pages10
JournalJournal of comparative effectiveness research
Issue number2
Publication statusPublished - Mar 11 2013



  • NIH
  • comparative effectiveness research
  • dissemination
  • implementation

ASJC Scopus subject areas

  • Health Policy

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