Dissecting risk haplotypes in sporadic Alzheimer's disease

Frank Soldner, Rudolf Jaenisch

Research output: Contribution to journalShort survey

5 Citations (Scopus)

Abstract

Understanding how genetic risk variants contribute to complex diseases is crucial for predicting disease susceptibility and developing patient-tailored therapies. In this issue of Cell Stem Cell, Young et al. (2015) dissect the function of common non-coding risk haplotypes in the SORL1 locus in the pathogenesis of sporadic Alzheimer's disease using patient-derived induced pluripotent stem cells.

Original languageEnglish (US)
Pages (from-to)341-342
Number of pages2
JournalCell Stem Cell
Volume16
Issue number4
DOIs
StatePublished - Apr 2 2015
Externally publishedYes

Fingerprint

Haplotypes
Alzheimer Disease
Induced Pluripotent Stem Cells
Disease Susceptibility
Stem Cells
Therapeutics

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

Cite this

Dissecting risk haplotypes in sporadic Alzheimer's disease. / Soldner, Frank; Jaenisch, Rudolf.

In: Cell Stem Cell, Vol. 16, No. 4, 02.04.2015, p. 341-342.

Research output: Contribution to journalShort survey

Soldner, Frank ; Jaenisch, Rudolf. / Dissecting risk haplotypes in sporadic Alzheimer's disease. In: Cell Stem Cell. 2015 ; Vol. 16, No. 4. pp. 341-342.
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