Discordant Uptake on Ga-67 and Tc-99m MDP Scintigraphy in a Patient with Multiple Myeloma

An Indication of Poor Prognosis

Tong Li, Jack Farinhas, Kwang J. Chun, Leonard M. Freeman

Research output: Contribution to journalArticle

Abstract

A 54-year-old woman with known stage IV multiple myeloma, proved by histologic analysis to be poorly differentiated plasma cell type 2 months earlier, was hospitalized for evaluation of persistent fever. Among other complications, stage IV sacral decubitus ulcers prompted Tc-99m MDP bone scintigraphy and subsequent Ga-67 scintigraphy for the evaluation of possible bone infection. Interestingly, bone infection was excluded, but there was more robust Ga-67 uptake compared with Tc-99m MDP. Previous reports in the literature suggest that this reflects fulminant disease with a poor prognosis.

Original languageEnglish (US)
Pages (from-to)322-324
Number of pages3
JournalClinical Nuclear Medicine
Volume28
Issue number4
DOIs
StatePublished - Apr 2003

Fingerprint

Technetium Tc 99m Medronate
Multiple Myeloma
Radionuclide Imaging
Bone and Bones
Pressure Ulcer
Infection
Plasma Cells
Fever

Keywords

  • Ga-67 Scintigraphy
  • Multiple Myeloma
  • Radiographic Skeletal Survey
  • Tc-99m MDP Bone Scintigraphy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

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abstract = "A 54-year-old woman with known stage IV multiple myeloma, proved by histologic analysis to be poorly differentiated plasma cell type 2 months earlier, was hospitalized for evaluation of persistent fever. Among other complications, stage IV sacral decubitus ulcers prompted Tc-99m MDP bone scintigraphy and subsequent Ga-67 scintigraphy for the evaluation of possible bone infection. Interestingly, bone infection was excluded, but there was more robust Ga-67 uptake compared with Tc-99m MDP. Previous reports in the literature suggest that this reflects fulminant disease with a poor prognosis.",
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AB - A 54-year-old woman with known stage IV multiple myeloma, proved by histologic analysis to be poorly differentiated plasma cell type 2 months earlier, was hospitalized for evaluation of persistent fever. Among other complications, stage IV sacral decubitus ulcers prompted Tc-99m MDP bone scintigraphy and subsequent Ga-67 scintigraphy for the evaluation of possible bone infection. Interestingly, bone infection was excluded, but there was more robust Ga-67 uptake compared with Tc-99m MDP. Previous reports in the literature suggest that this reflects fulminant disease with a poor prognosis.

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