Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

Jerome Mertens, Apuã C.M. Paquola, Manching Ku, Emily Hatch, Lena Böhnke, Shauheen Ladjevardi, Sean McGrath, Benjamin Campbell, Hyungjun Lee, Joseph R. Herdy, J. Tiago Gonçalves, Tomohisa Toda, Yongsung Kim, Jürgen Winkler, Jun Yao, Martin W. Hetzer, Fred H. Gage

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Medicine & Life Sciences