Dimethyl fumarate reduces TNF and Plasmodium falciparum induced brain endothelium activation in vitro

Agriculture & Biology

• dimethyl fumarate 100%
• tumor necrosis factors 69%
• Plasmodium falciparum 61%
• endothelium 54%
• cerebral malaria 52%
• endothelial cells 52%
• brain 36%
• parasites 25%
• therapeutics 10%
• central nervous system diseases 7%
• erythrocytes 7%
• peroxisome proliferator-activated receptors 6%
• encephalopathy 6%
• sclerosis 6%
• pediatrics 5%
• antimalarials 5%
• seizures 5%
• coculture 5%
• morbidity 4%
• central nervous system 4%
• oxidants 4%
• in vitro culture 4%
• inflammation 4%
• stress response 3%
• oxidative stress 3%
• transcription factors 3%
• Biological Sciences 3%
• drugs 3%
• assays 2%
• infection 2%
• methodology 1%

Medicine & Life Sciences

• Dimethyl Fumarate 80%
• Plasmodium falciparum 54%
• Endothelium 45%
• Cerebral Malaria 38%
• Endothelial Cells 38%
• Tumor Necrosis Factor-alpha 36%
• NF-E2-Related Factor 2 33%
• Parasites 31%
• Brain 25%
• In Vitro Techniques 22%
• human TNF protein 19%
• Brain Diseases 8%
• Erythrocytes 7%
• Peroxisome Proliferator-Activated Receptors 5%
• Brain Edema 5%
• Central Nervous System Diseases 5%
• Coculture Techniques 4%
• Multiple Sclerosis 4%
• Seizures 3%
• Interleukin-6 3%
• Transcription Factors 3%
• Antioxidants 3%
• Anti-Inflammatory Agents 3%
• Oxidative Stress 3%
• Up-Regulation 3%
• Down-Regulation 3%
• Pediatrics 3%
• Morbidity 2%
• Mortality 2%
• Therapeutics 2%
• Infections 2%
• Pharmaceutical Preparations 1%