Abstract
Protein sequences are often derived by translating genetic information, rather than by classical protein sequencing. At the DNA level cysteines and half cystines are indistinguishable. Here we show that the sequential environments of 'free' cysteine and half cystine are different. A possible origin of this difference is discussed and a simple method to predict cysteines and half cystines from the amino acid sequence is also presented.
Original language | English (US) |
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Pages (from-to) | 117-120 |
Number of pages | 4 |
Journal | FEBS Letters |
Volume | 302 |
Issue number | 2 |
DOIs | |
State | Published - May 11 1992 |
Externally published | Yes |
Keywords
- Free cysteine
- Half cystine
- Prediction
- Sequential environment
ASJC Scopus subject areas
- Biophysics
- Structural Biology
- Biochemistry
- Molecular Biology
- Genetics
- Cell Biology