TY - JOUR
T1 - Dietary Interventions for Weight Loss and Maintenance
T2 - Preference or Genetic Personalization?
AU - Wu, Hongyu
AU - Wylie-Rosett, Judith
AU - Qi, Qibin
N1 - Funding Information:
Judith Wylie-Rosett has received compensation from the Alliance for Potato Research and Education for serving as a board member; has received compensation from Omron for service as a consultant; is supported through a grant from the National Institutes of Health (NIH); and has received payment for lectures, including service on speakers’ bureaus from the Dairy Research Institute and Northwest Pear Research.
PY - 2013/12
Y1 - 2013/12
N2 - Obesity and related co-morbidities are major health problems throughout the world. Dietary interventions are the most common strategies employed for weight loss in overweight and obese individuals. A large body of evidence has shown that many diets varying in quantity and quality of macronutrients are effective in promoting weight loss, but there is still extensive debate about what types of diet are most effective for treating overweight and obesity. Likewise, long-term weight loss and maintenance are difficult for overweight and obese people. On the other hand, significant inter-individual variation in weight loss in response to dietary composition has long been noted, partly accounted for by an individual's genetic makeup. Identification of gene-diet interactions in weight loss may provide useful information for the development of personalized approaches to weight loss. This review summarizes dietary intervention studies for weight loss and maintenance, and recent studies of gene-diet interaction with regard to weight loss.
AB - Obesity and related co-morbidities are major health problems throughout the world. Dietary interventions are the most common strategies employed for weight loss in overweight and obese individuals. A large body of evidence has shown that many diets varying in quantity and quality of macronutrients are effective in promoting weight loss, but there is still extensive debate about what types of diet are most effective for treating overweight and obesity. Likewise, long-term weight loss and maintenance are difficult for overweight and obese people. On the other hand, significant inter-individual variation in weight loss in response to dietary composition has long been noted, partly accounted for by an individual's genetic makeup. Identification of gene-diet interactions in weight loss may provide useful information for the development of personalized approaches to weight loss. This review summarizes dietary intervention studies for weight loss and maintenance, and recent studies of gene-diet interaction with regard to weight loss.
KW - Dietary intervention
KW - Gene-diet interaction
KW - Obesity
KW - Weight loss
KW - Weight maintenance
UR - http://www.scopus.com/inward/record.url?scp=84962666351&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84962666351&partnerID=8YFLogxK
U2 - 10.1007/s13668-013-0061-3
DO - 10.1007/s13668-013-0061-3
M3 - Review article
AN - SCOPUS:84962666351
VL - 2
SP - 189
EP - 198
JO - Current Nutrition Reports
JF - Current Nutrition Reports
SN - 2161-3311
IS - 4
ER -
