Agentes virales asociados al sindrome diarreico en pacientes trasplantados renales

Translated title of the contribution: Diarrheic syndrome related to viral agents in kidney transplanted patients

Mildre C. Valle, Laura C. Martinez, Leonardo J. Ferreyra, Miguel O. Giordano, Maria B. Isa, Jorge V. Paván, Graciela De Boccardo, Pablo U. Massari, Silvia V. Nates

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The aim of this study was to report on the occurrence of conventional and emerging viral agents as well as their etiological link with diarrhea in kidney transplanted subjects from Cordoba, Argentina. A total of 42 stool samples were analysed. They were obtained from both ambulatory and hospitalized kidney transplanted patients with and without diarrhea after transplant. All patients were under immunosuppressive treatment with steroids, azatioprine and cyclosporine or tacrolimus. Results revealed the presence of group A rotavirus and picobirnavirus in three patients suffering from severe diarrhea (33.33%). No enteric bacterial agent was isolated from these patients. The presence of viral agents was related to high levels of cyclosporine in blood (> 290 ng/ml) or prolonged immunosuppressive treatment. On the other hand, no virus was detected in any of the samples collected from asymptomatic individuals (p <0.05). These findings suggest that viruses are implicated in the ethiology of diarrheal disease in these patients.

Original languageSpanish
Pages (from-to)179-182
Number of pages4
JournalMedicina
Volume61
Issue number2
StatePublished - Dec 1 2001

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Keywords

  • Adenovirus
  • Kidney transplant
  • Picobirnavirus
  • Rotavirus
  • Viral diarrhea

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Valle, M. C., Martinez, L. C., Ferreyra, L. J., Giordano, M. O., Isa, M. B., Paván, J. V., De Boccardo, G., Massari, P. U., & Nates, S. V. (2001). Agentes virales asociados al sindrome diarreico en pacientes trasplantados renales. Medicina, 61(2), 179-182.