KLINISCHE UND LABORCHEMISCHE UNTERSUCHUNGEN ZUR DIAGNOSTISCHEN ABGRENZUNG DER CHRONISCHEN LYMPHATISCHEN LEUKAMIE

Translated title of the contribution: Diagnostic definition of chronic lymphatic leukemia by clinical and laboratory investigations

J. F. Hofer, J. D. Schwarzmeier, L. Marosi, E. Paietta, T. Radaskiewicz

Research output: Contribution to journalArticle

Abstract

In its conventional meaning, chronic lymphatic leukemia (CLL) describes a variety of clinical and prognostical aspects. Since it was found, using immunohistological methods, that a remarkable number of lymphoplasmacytoid lymphomas (immunocytomas) were initially considered to belong to the CLL-group according to cell morphology, cell count and clinical status, the purpose of this study was to set up clinical and laboratory parameters separating CLL and immunocytoma. This was accomplished by categorizing 71 patients of preliminary CLL by age, sex, distribution of B and T lymphocytes, cell morphology, symptoms at the time of diagnosis, clinical course, electrophoresis and quantitative immunglobulin. According to these features, the sample of patients was divided into three groups: Group 1: chronic lymphatic leukemia probable. Group 2: immunocytoma probable. Group 3: a clear-cut separation is not possible. In these patients a lymphnode extirpation and a fluorescent examination of surface immunglobulin should be performed.

Original languageGerman
Pages (from-to)222-225
Number of pages4
JournalActa Medica Austriaca
Volume6
Issue number5
StatePublished - Dec 1 1979
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

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