Abstract
Abdominal aortic aneurysms (AAAs) are a significant cause of morbidity and mortality worldwide whose incidence is increasing. Traditionally these aneurysms have been repaired by a standard surgical approach. Over the past decade, spurred by the development of endovascular therapies for a variety of vascular pathologies, the endoluminal treatment of AAAs has rapidly proliferated. Early stent-grafts used to treat AAAs were primarily 'home-made'. Presently there are a number of industry-made devices available on both an investigational and approved for use basis and the number is growing. This review focuses on the types of stent-grafts currently available, indications for use and patient selection, as well as new patents issued over the years 1998 - 2000. The ideal stent-graft is yet to be developed and not all AAAs are amenable to endovascular treatment. This is a dynamic field where developments are likely to continue at a rapid pace.
Original language | English (US) |
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Pages (from-to) | 747-763 |
Number of pages | 17 |
Journal | Expert Opinion on Therapeutic Patents |
Volume | 11 |
Issue number | 5 |
DOIs | |
State | Published - 2001 |
Keywords
- Abdominal aortic aneurysm (AAA)
- Devices
- Endoluminal
- Endovascular
- Morphology
- Stent
- Stent-graft
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery